Argonne National Laboratory

GM/CA @ APS

Users Publications

Department of Energy Office of Science
GM/CA @ APS Sponsors:
National Institute of General Medical Sciences (NIGMS) and National Cancer Institute (NCI) of the National Institutes of Health (NIH)
 
Sector: 23 GM/CA-XSD
Number of Records: 1293
Ryan G. Walker, Magdalena Czepnik, Erich J. Goebel, Jason C. McCoy, Ana Vujic, Miook Cho, Juhyun Oh, Senem Aykul, Kelly L. Walton, Gauthier Schang, Daniel J. Bernard, Andrew P. Hinck, Craig A. Harrison, Erik Martinez-Hackert, Amy J. Wagers, Richard T. Lee, Thomas B. Thompson, "Structural basis for potency differences between GDF8 and GDF11," BMC Biology 15, 19-1-19-22 (2017). DOI: 10.1186/s12915-017-0350-1

Zinaida Polonskaya, Shenglou Deng, Anita Sarkar, Lisa Kain, Marta Comellas-Aragones, Craig S. McKay, Katarzyna Kaczanowska, Marie Holt, Ryan McBride, Valle Palomo, Kevin M. Self, Seth Taylor, Adriana Irimia, Sanjay R. Mehta, Jennifer M. Dan, Matthew Brigger, Shane Crotty, Stephen P. Schoenberger, James C. Paulson, Ian A. Wilson, Paul B. Savage, M.G. Finn, Luc Teyton, "T cells control the generation of nanomolar-affinity anti-glycan antibodies," J. Clin. Invest. 127 (4), 1491-1504 (2017). DOI: 10.1172/JCI91192

Megan P.D. Zahniser, Shreenath Prasad, Malea M. Kneen, Cheryl A. Kreinbring, Gregory A. Petsko, Dagmar Ringe, Michael J. McLeish, "Structure and mechanism of benzaldehyde dehydrogenase from Pseudomonas putida ATCC 12633, a member of the Class 3 aldehyde dehydrogenase superfamily," Protein Eng. Des. Sel. 30 (3), 271-278 (2017). DOI: https://doi.org/10.1093/protein/gzx015

Meriem El Ghachi, Nicole Howe, Rodolphe Auger, Alexandre Lambion, Annick Guiseppi, François Delbrassine, Guillaume Manat, Sophie Roure, Sabine Peslier, Eric Sauvage, Lutz Vogeley, Juan-Carlos Rengifo-Gonzalez, Paulette Charlier, Dominique Mengin-Lecreulx, Maryline Foglino, Thierry Touzé, Martin Caffrey, Frédéric Kerff, "Crystal structure and biochemical characterization of the transmembrane PAP2 type phosphatidylglycerol phosphate phosphatase from Bacillus subtilis," Cell Mol. Life Sci. 74 (12), 2319-2332 (2017). DOI: 10.1007/s00018-017-2464-6

Jacqueline L. Naffin-Olivos, Andrew Daab, Andre White, Nathan E. Goldfarb, Amy C. Milne, Dali Liu, Jacqueline Baikovitz, Ben M. Dunn, Jyothi Rengarajan, Gregory A. Petsko, Dagmar Ringe, "Structure Determination of Mycobacterium tuberculosis Serine Protease Hip1 (Rv2224c)," Biochemistry-US 56 (17), 2304-2314 (2017). DOI: 10.1021/acs.biochem.6b01066

Gabriel Pascual, Jehangir S. Wadia, Xueyong Zhu, Elissa Keogh, Başak Kükrer, Jeroen van Ameijde, Hanna Inganäs, Berdien Siregar, Gerrard Perdok, Otto Diefenbach, Tariq Nahar, Imke Sprengers, Martin H. Koldijk, Els C. Brinkman-van der Linden, Laura A. Peferoen, Heng Zhang, Wenli Yu, Xinyi Li, Michelle Wagner, Veronica Moreno, Julie Kim, Martha Costa, Kiana West, Zara Fulton, Lucy Chammas, Nancy Luckashenak, Lauren Fletcher, Trevin Holland, Carrie Arnold, R. Anthony Williamson, Jeroen J. Hoozemans, Adrian Apetri, Frederique Bard, Ian A. Wilson, Wouter Koudstaal, Jaap Goudsmit, "Immunological memory to hyperphosphorylated tau in asymptomatic individuals," Acta Neuropathol. 133 (5), 767-783 (2017). DOI: 10.1007/s00401-017-1705-y

Jeremy M. Schieferstein, Ashtamurthy S. Pawate, Chang Sun, Frank Wan, Paige N. Sheraden, Jana Broecker, Oliver P. Ernst, Robert B. Gennis, Paul J.A. Kenis, "X-ray transparent microfluidic chips for high-throughput screening and optimization of in meso membrane protein crystallization," Bioinformatics 11 (2), 024118-1-024118-13 (2017). DOI: 10.1063/1.4981818

Jeong Hyun Lee, Raiees Andrabi, Ching-Yao Su, Anila Yasmeen, Jean-Philippe Julien, Leopold Kong, Nicholas C. Wu, Ryan McBride, Devin Sok, Matthias Pauthner, Christopher A. Cottrell, Travis Nieusma, Claudia Blattner, James C. Paulson, Per Johan Klasse, Ian A. Wilson, Dennis R. Burton, Andrew B. Ward, "A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic [beta]-Hairpin Structure," Immunity 46 (4), 690-702 (2017). DOI: 10.1016/j.immuni.2017.03.017

Rui Wu, Ruslan Sanishvili, Boris R. Belitsky, Jose I. Juncosa, Hoang V. Le, Helaina J.S. Lehrer, Michael Farley, Richard B. Silverman, Gregory A. Petsko, Dagmar Ringe, Dali Liu, "PLP and GABA trigger GabR-mediated transcription regulation in Bacillus subtilis via external aldimine formation," Proc. Natl. Acad. Sci. USA 114 (15), 3891-3896 (2017). DOI: 10.1073/pnas.1703019114

Orville A. Pemberton, Xiujun Zhang, Yu Chen, "Molecular Basis of Substrate Recognition and Product Release by the Klebsiella pneumoniae Carbapenemase (KPC-2)," J. Med. Chem. 60 (8), 3525-3530 (2017). DOI: 10.1021/acs.jmedchem.7b00158

Rongxin Nie, Steven Stark, Jindrich Symersky, Ronald S. Kaplan, Min Lu, "Structure and function of the divalent anion/Na þ symporter from Vibrio cholerae and a humanized variant," Nat. Commun. 8, 15009-1-15009-10 (2017). DOI: 10.1038/ncomms15009

Haitao Zhang, Gye Won Han, Alexander Batyuk, Andrii Ishchenko, Kate L. White, Nilkanth Patel, Anastasiia Sadybekov, Beata Zamlynny, Michael T. Rudd, Kaspar Hollenstein, Alexandra Tolstikova, Thomas A. White, Mark S. Hunter, Uwe Weierstall, Wei Liu, Kerim Babaoglu, Eric L. Moore, Ryan D. Katz, Jennifer M. Shipman, Margarita Garcia-Calvo, Sujata Sharma, Payal Sheth, Stephen M. Soisson, Raymond C. Stevens, Vsevolod Katritch, Vadim Cherezov , "Structural basis for selectivity and diversity in angiotensin II receptors," Nature 544, 327-332 (2017). DOI: 10.1038/nature22035

Jing Tang, Karen A. Kirby, Andrew D. Huber, Mary C. Casey, Juan Ji, Daniel J. Wilson, Stefan G. Sarafianos, Zhengqiang Wang, "6-Cyclohexylmethyl-3-hydroxypyrimidine-2,4-dione as an inhibitor scaffold of HIV reverase transcriptase: Impacts of the 3-OH on inhibiting RNase H and polymerase," Eur. J. Med. Chem. 128, 168-179 (2017). DOI: 10.1016/j.ejmech.2017.01.041

Vincent C. Luca, Byoung Choul Kim, Chenghao Ge, Shinako Kakuda, Di Wu, Mehdi Roein-Peikar, Robert S. Haltiwanger, Cheng Zhu, Taekjip Ha, K. Christopher Garcia, "Notch-Jagged complex structure implicates a catch bond in tuning ligand sensitivity," Science 355, 1320-1324 (2017). DOI: 10.1126/science.aaf9739

Walter R.P. Novak, Basudeb Bhattacharyya, Daniel P. Grilley, Todd M. Weaver, "Proteolysis of truncated hemolysin A yields a stable dimerization interface," Acta Crystallogr. F 73 (3), 138-145 (2017). DOI: 10.1107/S2053230X17002102

Roger Tseng, Nicolette F. Goularte, Archana Chavan, Jansen Luu, Susan E. Cohen, Yong-Gang Chang, Joel Heisler, Sheng Li, Alicia K. Michael, Sarvind Tripathi, Susan S. Golden, Andy LiWang, Carrie L. Partch, "Structural basis of the day-night transition in a bacterial circadian clock," Science 355, 1174-1180 (2017). DOI: 10.1126/science.aag2516 .

Jacob L.W. Morgan, Justin F. Acheson, Jochen Zimmer, "Structure of a Type-1 Secretion System ABC Transporter," Structure 25 (3), 522-529 (2017). DOI: 10.1016/j.str.2017.01.010

Iebe Rossey, Morgan S.A. Gilman, Stephanie C. Kabeche, Koen Sedeyn, Daniel Wrapp, Masaru Kanekiyo, Man Chen, Vicente Mas, Jan Spitaels, José A. Melero, Barney S. Graham, Bert Schepens, Jason S. McLellan, Xavier Saelens, "Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state," Nat. Commun. 8, 14158-1-14158-12 (2017). DOI: 10.1038/ncomms14158

Asim K Bera, Kelly G. Aukema, Mikael Elias, Lawrence P. Wackett, "Structure of the Cyanuric Acid Hydrolase TrzD Reveals Product Exit Channel," Sci. Rep. 7, 45277-1-45277-9 (2017). DOI: 10.1038/srep45277

Kathleen M. Clark, Jermaine L. Jenkins, Nadia Fedoriw, Mark E. Dumont, "Human CaaX protease ZMPSTE24 expressed in yeast: Structure and inhibition by HIV protease inhibitors," Protein Sci. 26 (2), 242-257 (2017). DOI: 10.1002/pro.3074

Xianchi Dong, Bo Zhao, Roxana E. Iacob, Jianghai Zhu, Adem C. Koksal, Chafen Lu, John R. Engen, Timothy A. Springer , "Force interacts with macromolecular structure in activation of TGF-[beta]," Nature 542, 55-59 (2017). DOI: 10.1038/nature21035

Meng S. Choy, Yang Li, Luciana E.S.F. Machado, Micha B.A. Kunze, Christopher R. Connors, Xingyu Wei, Kresten Lindorff-Larsen, Rebecca Page, Wolfgang Peti, "Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery," Mol. Cell 65 (4), 644-658 (2017). DOI: 10.1016/j.molcel.2017.01.014

Julie M. Grondin, Da Duan, Alyssa C. Kirlin, Kento T. Abe, Seth Chitayat, Holly L. Spencer, Craig Spencer, Alisha Campigotto, Scott Houliston, Cheryl H. Arrowsmith, John S. Allingham, Alisdair B. Boraston, Steven P. Smith, "Diverse modes of galacto-specific carbohydrate recognition by a family 31 glycoside hydrolase from Clostridium perfringens," PLoS One 12 (2), e0171606-1-e0171606-18 (2017). DOI: 10.1371/journal.pone.0171606

Adriana Irimia, Andreia M. Serra, Anita Sarkar, Ronald Jacak, Oleksandr Kalyuzhniy, Devin Sok, Karen L. Saye-Francisco, Torben Schiffner, Ryan Tingle, Michael Kubitz, Yumiko Adachi, Robyn L. Stanfield, Marc C. Deller, Dennis R. Burton, William R. Schief, Ian A. Wilson, "Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design," PLoS Patho. 13 (2), e1006212-1-e1006212-20 (2017). DOI: 10.1371/journal.ppat.1006212

Wupeng Yan, Everett Stone, Yan Jessie Zhang, "Structural Snapshots of an Engineered Cystathionine-[gamma]-lyase Reveal the Critical Role of Electrostatic Interactions in the Active Site," Biochemistry-US 56 (6), 876-885 (2017). DOI: 10.1021/acs.biochem.6b01172

Jana Broecker, Bryan T. Eger, Oliver P. Ernst, "Crystallogenesis of Membrane Proteins Mediated by Polymer-Bounded Lipid Nanodiscs," Structure 25 (2), 384-392 (2017). DOI: 10.1016/j.str.2016.12.004

Bingfa Sun, Priti Bachhawat, Matthew Ling-Hon Chu, Martyn Wood, Tom Ceska, Zara A. Sands, Joel Mercier, Florence Lebon, Tong Sun Kobilka, Brian K. Kobilka, "Crystal structure of the adenosine A[subscript 2A] receptor bound to an antagonist reveals a potential allosteric pocket," Proc. Natl. Acad. Sci. USA 114 (8), 2066-2071 (2017). DOI: 10.1073/pnas.1621423114

Kinlin L. Chao, Liudmila Kulakova, Osnat Herzberg, "Gene polymorphism linked to increased asthma and IBD risk alters gasdermin-B structure, a sulfatide and phosphoinositide binding protein," Proc. Natl. Acad. Sci. USA 114 (7), 1128-1137 (2017). DOI: 10.1073/pnas.1616783114

Nobuhisa Watanabe, Takayuki Nagae, Yusuke Yamada, Ayana Tomita, Naohiro Matsugaki, Masao Tabuchi, "Protein crystallography beamline BL2S1 at the Aichi synchrotron," J. Synchrotron Rad. 24 (1), 338-343 (2017). DOI: 10.1107/S1600577516018579

Jessica F. Bruhn, Robert N. Kirchdoerfer, Sarah M. Urata, Sheng Li, Ian J. Tickle, Gérard Bricogne, Erica Ollmann Saphire, "Crystal Structure of the Marburg Virus VP35 Oligomerization Domain," J. Virol. 91 (2), e01085-1-e01085-16 (2017). DOI: 10.1128/JVI.01085-16

Daniel Wacker, Sheng Wang, John D. McCorvy, Robin M. Betz, A.J. Venkatakrishnan, Anat Levit, Katherine Lansu, Zachary L. Schools, Tao Che, David E. Nichols, Brian K. Shoichet, Ron O. Dror, Bryan L. Roth, "Crystal Structure of an LSD-Bound Human Serotonin Receptor," Cell 168 (3), 377-389 (2017). DOI: 10.1016/j.cell.2016.12.033

Nicole M. Scarborough, G.M. Dilshan P. Godaliyadda, Dong Hye Ye, David J. Kissick, Shijie Zhang, Justin A. Newman, Michael J. Sheedlo, Azhad U. Chowdhury, Robert F. Fischetti, Chittaranjan Das, Gregery T. Buzzard, Charles A. Bouman, Garth J. Simpson, "Dynamic X-ray diffraction sampling for protein crystal positioning," J. Synchrotron Rad. 24 (1), 188-195 (2017). DOI: 10.1107/S160057751601612X

Phillip S. Rushton, Anna T. Olek, Lee Makowski, John Badger, C. Nicklaus Steussy, Nicholas C. Carpita, Cynthia V. Stauffacher, "Rice Cellulose SynthaseA8 Plant-Conserved Region Is a Coiled-Coil at the Catalytic Core Entrance," Plant Physiol. 173 (1), 482-494 (2017). DOI: ​10.​1104/​pp.​16.​00739

Jiangtao Guo, Weizhong Zeng, Youxing Jiang, "Tuning the ion selectivity of two-pore channels," Proc. Natl. Acad. Sci. USA 114 (5), 1009-1014 (2017). DOI: 10.1073/pnas.1616191114

Rameshwar U. Kadam, Ian A. Wilson, "Structural basis of influenza virus fusion inhibition by the antiviral drug Arbidol," Proc. Natl. Acad. Sci. USA 114 (2), 206-214 (2017). DOI: 10.1073/pnas.1617020114

Tengchuan Jin, Watchalee Chuenchor, Jiansheng Jiang, Jinbo Cheng, Yajuan Li, Kang Fang, Mo Huang, Patrick Smith, Tsan Sam Xiao, "Design of an expression system to enhance MBP-mediated crystallization," Sci. Rep. 7, 40991-1-40991-11 (2017). DOI: 10.1038/srep40991

Walter A. Bogdanoff, Jocelyn Campos, Edmundo I. Perez, Lu Yin, David L. Alexander, Rebecca M. DuBois, "Structure of a Human Astrovirus Capsid-Antibody Complex and Mechanistic Insights into Virus Neutralization," J. Virol. 91 (2), e01859-1-e01859-12 (2017). DOI: 10.1128/JVI.01859-16

Catherine L. Shelton, Deborah G. Conrady, Andrew B. Herr, "Functional consequences of B-repeat sequence variation in the staphylococcal biofilm protein Aap: deciphering the assembly code," Biochem. J. 474 (3), 427-443 (2017). DOI: 10.1042/BCJ20160675

Chao Xu, Hideaki Ishikawa, Keiichi Izumikawa, Li Li, Hao He, Yuko Nobe, Yoshio Yamauchi, Hanief M. Shahjee, Xian-Hui Wu, Yi-tao Yu, Toshiaki Isobe, Nobuhiro Takahashi, Jinrong Min, "Structural insights into Gemin5-guided selection of pre-snRNAs for snRNP assembly," Gene Dev. 30, 2376-2390 (2016). DOI: 10.1101/gad.288340.116

W. Clay Brown, David L. Akey, Jamie R. Konwerski, Jeffrey T. Tarrasch, Georgios Skiniotis, Richard J. Kuhn, Janet L. Smith , "Extended surface for membrane association in Zika virus NS1 structure," Nat. Struct. Mol. Biol. 23, 865-867 (2016). DOI: 10.1038/nsmb.3268

Jörn Viell, Hideyo Inouye, Noemi K. Szekely, Henrich Frielinghaus, Caroline Marks, Yumei Wang, Nico Anders, Antje C. Spiess, Lee Makowski, "Multi-scale processes of beech wood disintegration and pretreatment with 1-ethyl-3-methylimidazolium acetate/water mixtures," Biotechnol. Biofuels 9, 7-1-7-15 (2016). DOI: 10.1186/s13068-015-0422-9

Sharon L. Guffy, Bryan S. Der, Brian Kuhlman, "Probing the minimal determinants of zinc binding with computational protein design," Protein Eng. Des. Sel. 29 (8), 327-338 (2016). DOI: https://doi.org/10.1093/protein/gzw026

Brad C. Bennett, Michael D. Purdy, Kent A. Baker, Chayan Acharya, William E. McIntire, Raymond C. Stevens, Qinghai Zhang, Andrew L. Harris, Ruben Abagyan, Mark Yeager , "An electrostatic mechanism for Ca[superscript 2+]-mediated regulation of gap junction channels," Nat. Commun. 7, 8770-1-8770-12 (2016). DOI: 10.1038/ncomms9770

Amanda J. Martinot, Mary Farrow, Lu Bai, Emilie Layre, Tan-Yun Cheng, Jennifer H. Tsai, Jahangir Iqbal, John W. Annand, Zuri A. Sullivan, M. Mahmood Hussain, James Sacchettini, D. Branch Moody, Jessica C. Seeliger, "Mycobacterial Metabolic Syndrome: LprG and Rv1410 Regulate Triacylglyceride Levels, Growth Rate and Virulence in Mycobacterium tuberculosis," PLoS Patho. 12 (1), e1005351-1-e1005351-26 (2016). DOI: 10.1371/journal.ppat.1005351

Nicholas D. Mullins, Nuala M. Maguire, Alan Ford, Kalyan Das, Eddy Arnold, Jan Balzarini, Anita R. Maguire, "Exploring the role of the [alpha]-carboxyphosphonate moiety in the HIV-RT activity of [alpha]-carboxy nucleoside phosphonates," Org. Biomol. Chem. 14 (8), 2452-2465 (2016). DOI: 10.1039/C5OB02507A

Tirtha Mandal, Seungjin Shin, Sreevidya Aluvila, Hui-Chen Chen, Carter Grieve, Jun-Yong Choe, Emily H. Cheng, Eric J. Hustedt, Kyoung Joon Oh, "Assembly of Bak homodimers into higher order homooligomers in the mitochondrial apoptotic pore," Sci. Rep. 6, 30763-1-30763-14 (2016). DOI: 10.1038/srep30763

Xiaolong Lu, Konstantin R. Malley, Caitlin C. Brenner, Olga Koroleva, Sergey Korolev, Brian P. Downes, "A MUB E2 structure reveals E1 selectivity between cognate ubiquitin E2s in eukaryotes," Nat. Commun. 7, 12580 -1 (2016). DOI: 10.1038/ncomms12580

Jiliang Liu, Isabel Costantino, Nagarajan Venugopalan, Robert F. Fischetti, Bradley T. Hyman, Matthew P. Frosch, Teresa Gomez-Isla, Lee Makowski, "Amyloid structure exhibits polymorphism on multiple length scales in human brain tissue," Sci. Rep. 6, 33079-1-33079-11 (2016). DOI: 10.1038/srep33079

Jiliang Liu, Jeong Im Kim, Joanne C. Cusumano, Clint Chapple, Nagarajan Venugopalan, Robert F. Fischetti, Lee Makowski, "The impact of alterations in lignin deposition on cellulose organization of the plant cell wall," Biotechnol. Biofuels 9, 126-1-126-17 (2016). DOI: 10.1186/s13068-016-0540-z

Annabel Romero-Hernandez, Noriko Simorowski, Erkan Karakas, Hiro Furukawa, "Molecular Basis for Subtype Specificity and High-Affinity Zinc Inhibition in the GluN1-GluN2A NMDA Receptor Amino-Terminal Domain," Neuron 92 (6), 1324-1336 (2016). DOI: 10.1016/j.neuron.2016.11.006

Brian E. Krumm, Sangbae Lee, Supriyo Bhattacharya, Istvan Botos, Courtney F. White, Haijuan Du, Nagarajan Vaidehi, Reinhard Grisshammer, "Structure and dynamics of a constitutively active neurotensin receptor," Sci. Rep. 6, 38564-1-38564-15 (2016). DOI: 10.1038/srep38564

Mukta D. Khasnis, Konstantine Halkidis¤, Anshul Bhardwaj, Michael J. Root, "Receptor Activation of HIV-1 Env Leads to Asymmetric Exposure of the gp41 Trimer," PLoS Patho. 12 (12), e1006098-1-e1006098-29 (2016). DOI: 10.1371/journal.ppat.1006098

Zhenhua Shao, Jie Yin, Karen Chapman, Magdalena Grzemska, Lindsay Clark, Junmei Wang, Daniel M. Rosenbaum , "High-resolution crystal structure of the human CB1 cannabinoid receptor," Nature 540, 602-606 (2016). DOI: 10.1038/nature20613

Ayaka Harada, Yukari Sato, Naofumi Kamimura, Nagarajan Venugopalan, Eiji Masai, Toshiya Senda, "Overcoming a hemihedral twinning problem in tetra­hydrofolate-dependent O-de­methylase crystals by the microseeding method," Acta Crystallogr. F 72 (12), 897-902 (2016). DOI: 10.1107/S2053230X16018665

Meredith A. Skiba, Andrew P. Sikkema, William D. Fiers, William H. Gerwick, David H. Sherman, Courtney C. Aldrich, Janet L. Smith, "Domain Organization and Active Site Architecture of a Polyketide Synthase C-methyltransferase," ACS Chem. Biol. 11 (12), 3319-3327 (2016). DOI: 10.1021/acschembio.6b00759

Shouqiang Cheng, Alpay B. Seven, Jing Wang, Georgios Skiniotis, Engin Özkan, "Conformational Plasticity in the Transsynaptic Neurexin-Cerebellin-Glutamate Receptor Adhesion Complex," Structure 24 (12), 2163-2173 (2016). DOI: 10.1016/j.str.2016.11.004

Brandon R. Goblirsch, Matthew R. Jensen, Fatuma A. Mohamed, Lawrence P. Wackett, Carrie M. Wilmot, "Substrate Trapping in Crystals of the Thiolase OleA Identifies Three Channels That Enable Long Chain Olefin Biosynthesis," J. Biol. Chem. 291 (52), 26698-26706 (2016). DOI: 10.1074/jbc.M116.760892

Dahai Gai, Damian Wang, Shu-Xing Li, Xiaojiang S. Chen, "The structure of SV40 large T hexameric helicase in complex with AT-rich origin DNA," eLIFE J. 6, e18129-1-e18129-18 (2016). DOI: 10.7554/eLife.18129

William D. Fiers, Greg J. Dodge, David H. Sherman, Janet L. Smith, Courtney C. Aldrich, "Vinylogous Dehydration by a Polyketide Dehydratase Domain in Curacin Biosynthesis," J. Am. Chem. Soc. 138 (49), 16024-16036 (2016). DOI: 10.1021/jacs.6b09748

Yi Zheng, Ling Qin, Natalia V. Ortiz Zacarías, Henk de Vries, Gye Won Han, Martin Gustavsson, Marta Dabros, Chunxia Zhao, Robert J. Cherney, Percy Carter, Dean Stamos, Ruben Abagyan, Vadim Cherezov, Raymond C. Stevens, Adriaan P. IJzerman, Laura H. Heitman, Andrew Tebben, Irina Kufareva, Tracy M. Handel , "Structure of CC chemokine receptor 2 with orthosteric and allosteric antagonists," Nature 540, 458-461 (2016). DOI: 10.1038/nature20605

Hsiao-Ling Huang, Inna V. Krieger, Maloy K. Parai, Vijay B. Gawandi, James C. Sacchettini, "Mycobacterium tuberculosis Malate Synthase Structures with Fragments Reveal a Portal for Substrate/Product Exchange," J. Biol. Chem. 291 (53), 27421-27432 (2016). DOI: 10.1074/jbc.M116.750877

Kanghyun Lee, Ruchika Sharma, Om Kumar Shrestha, Craig A. Bingman, Elizabeth A. Craig , "Dual interaction of the Hsp70 J-protein cochaperone Zuotin with the 40S and 60S ribosomal subunits," Nat. Struct. Mol. Biol. 23 (11), 1003-1010 (2016). DOI: 10.1038/nsmb.3299

George Vaisey, Alexandria N. Miller, Stephen B. Long, "Distinct regions that control ion selectivity and calcium-dependent activation in the bestrophin ion channel," Proc. Natl. Acad. Sci. USA 113 (47), E7399-E7408 (2016). DOI: 10.1073/pnas.1614688113

Vannakambadi K. Ganesh, Xiaowen Liang, Joan A. Geoghegan, Ana Luisa V. Cohen, Nagarajan Venugopalan, Timothy J. Foster, Magnus Hook, "Lessons from the Crystal Structure of the S. aureus Surface Protein Clumping Factor A in Complex With Tefibazumab, an Inhibiting Monoclonal Antibody," EBioMedicine 13, 328-338 (2016). DOI: 10.1016/j.ebiom.2016.09.027

Jana Broecker, Viviane Klingel, Wei-Lin Ou, Aidin R. Balo, David J. Kissick, Craig M. Ogata, Anling Kuo, Oliver P. Ernst, "A Versatile System for High-Throughput In Situ X-ray Screening and Data Collection of Soluble and Membrane-Protein Crystals," Cryst. Growth Des. 16 (11), 6318-6326 (2016). DOI: 10.1021/acs.cgd.6b00950

Brandon Zimmerman, Brendan Kelly, Brian J. McMillan, Tom C.M. Seegar, Ron O. Dror, Andrew C. Kruse, Stephen C. Blacklow, "Crystal Structure of a Full-Length Human Tetraspanin Reveals a Cholesterol-Binding Pocket," Cell 167 (4), 1041-1051 (2016). DOI: 10.1016/j.cell.2016.09.056

Michiko Tawada, Shinkichi Suzuki, Yasuhiro Imaeda, Hideyuki Oki, Gyorgy Snell, Craig A. Behnke, Mitsuyo Kondo, Naoki Tarui, Toshimasa Tanaka, Takanobu Kuroita, Masaki Tomimoto, "Novel approach of fragment-based lead discovery applied to renin inhibitors," Bioorgan. Med. Chem. 24 (22), 6066-6074 (2016). DOI: 10.1016/j.bmc.2016.09.065

Laura M.K. Dassama, Grace E. Kenney, Soo Y. Ro, Eliza L. Zielazinski, Amy C. Rosenzweig, "Methanobactin transport machinery," Proc. Natl. Acad. Sci. USA 113 (46), 13027-13032 (2016). DOI: 10.1073/pnas.1603578113

Andrei Fokine, Michael G. Rossmann, "Common Evolutionary Origin of Procapsid Proteases, Phage Tail Tubes, and Tubes of Bacterial Type VI Secretion Systems," Structure 24 (11), 1928-1935 (2016). DOI: 10.1016/j.str.2016.08.013

Yasuhiro Imaeda, Michiko Tawada, Shinkichi Suzuki, Masaki Tomimoto, Mitsuyo Kondo, Naoki Tarui, Tsukasa Sanada, Ray Kanagawa, Gyorgy Snell, Craig A. Behnke, Keiji Kubo, Takanobu Kuroita, "Structure-based design of a new series of N-(piperidin-3-yl)pyrimidine-5-carboxamides as renin inhibitors," Bioorgan. Med. Chem. 24 (22), 5771-5780 (2016). DOI: 10.1016/j.bmc.2016.09.030

Olga Rechkoblit, Yogesh K. Gupta, Radhika Malik, Kanagalaghatta R. Rajashankar, Robert E. Johnson, Louise Prakash, Satya Prakash, Aneel K. Aggarwal, "Structure and mechanism of human PrimPol, a DNA polymerase with primase activity," Sci. Advances 2 (10), e1601317-1-e1601317-8 (2016). DOI: 10.1126/sciadv.1601317

Leo C.T. Ng, Igor Putrenko, Victoria Baronas, Filip Van Petegem, Eric A. Accili, "Cyclic Purine and Pyrimidine Nucleotides Bind to the HCN2 Ion Channel and Variably Promote C-Terminal Domain Interactions and Opening," Structure 24 (10), 1629-1642 (2016). DOI: 10.1016/j.str.2016.06.024

Travis Eisemann, Michael McCauley, Marie-France Langelier, Kushol Gupta, Swati Roy, Gregory D. Van Duyne, John M. Pascal, "Tankyrase-1 Ankyrin Repeats Form an Adaptable Binding Platform for Targets of ADP-Ribose Modification," Structure 24 (10), 1679-1692 (2016). DOI: 10.1016/j.str.2016.07.014

Benjamin J. Orlando, Michael G. Malkowski, "Crystal structure of rofecoxib bound to human cyclooxygenase-2," Acta Crystallogr. F 72 (10), 772-776 (2016). DOI: 10.1107/S2053230X16014230

Ce Feng Liu, Gabriel S. Brandt, Quyen Q. Hoang, Natalia Naumova, Vanja Lazarevic, Eun Sook Hwang, Job Dekker, Laurie H. Glimcher, Dagmar Ringe, Gregory A. Petsko, "Crystal structure of the DNA binding domain of the transcription factor T-bet suggests simultaneous recognition of distant genome sites," Proc. Natl. Acad. Sci. USA 113 (43), E6572-E6581 (2016). DOI: 10.1073/pnas.1613914113

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Yongheng Chen, Xiaojun Zhang, Ana Carolina Dantas Machado, Yuan Ding, Zhuchu Chen, Peter Z. Qin, Remo Rohs, Lin Chen, "Structure of p53 binding to the BAX response element reveals DNA unwinding and compression to accommodate base-pair insertion," Nucleic Acids Res. 41 (17), 8368-8376 (2013). DOI: 10.1093/nar/gkt584

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Yunji Wu, Anthony P. West, Jr., Helen J. Kim, Matthew E. Thornton, Andrew B. Ward, Pamela J. Bjorkman, "Structural Basis for Enhanced HIV-1 Neutralization by a Dimeric Immunoglobulin G Form of the Glycan-Recognizing Antibody 2G12," Cell Reports 5 (5), 1443-1455 (2013). DOI: 10.1016/j.celrep.2013.11.015

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Vidya Mangala Prasad, Steven D. Willows, Andrei Fokine, Anthony J. Battisti, Siyang Sun, Pavel Plevka, Tom C. Hobman, Michael G. Rossmann, "Rubella virus capsid protein structure and its role in virus assembly and infection," Proc. Natl. Acad. Sci. USA 110 (50), 20105-20110 (2013). DOI: 10.1073/pnas.1316681110

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Michael L. Oldham, Shanshuang Chen, Jue Chen, "Structural basis for substrate specificity in the Escherichia coli maltose transport system," Proc. Natl. Acad. Sci. USA 110 (45), 18132-18137 (2013). DOI: 10.1073/pnas.1311407110

Jonathan R. Whicher, Sarah S. Smaga, Douglas A. Hansen, William C. Brown, William H. Gerwick, David H. Sherman, Janet L. Smith, "Cyanobacterial Polyketide Synthase Docking Domains: A Tool for Engineering Natural Product Biosynthesis," Chem. Biol. 20 (11), 1340-1351 (2013). DOI: 10.1016/j.chembiol.2013.09.015

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Cristina V. Iancu, Jamillah Zamoon, Sang Bum Woo, Alexander Aleshin, Jun-yong Choe, "Crystal structure of a glucose/H[superscript +] symporter and its mechanism of action," Proc. Natl. Acad. Sci. USA 110 (44), 17862-17867 (2013). DOI: 10.1073/pnas.1311485110

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Judith A. Ronau, Lake N. Paul, Julian E. Fuchs, Isaac R. Corn, Kyle T. Wagner, Klaus R. Liedl, Mahdi M. Abu-Omar, Chittaranjan Das, "An additional substrate binding site in a bacterial phenylalanine hydroxylase," Eur. Biophys. J. 42 (9), 691-708 (2013). DOI: 10.1007/s00249-013-0919-8

Masanori Okaniwa, Masaaki Hirose, Takeo Arita, Masato Yabuki, Akito Nakamura, Terufumi Takagi, Tomohiro Kawamoto, Noriko Uchiyama, Akihiko Sumita, Shunichirou Tsutsumi, Tsuneaki Tottori, Yoshitaka Inui, Bi-Ching Sang, Jason Yano, Kathleen Aertgeerts, Sei Yoshida, Tomoyasu Ishikawa, "Discovery of a Selective Kinase Inhibitor (TAK-632) Targeting Pan-RAF Inhibition: Design, Synthesis, and Biological Evaluation of C-7-Substituted 1,3-Benzothiazole Derivatives," J. Med. Chem. 56 (16), 6478-6494 (2013). DOI: 10.1021/jm400778d

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Kristof Nolan, Chandramohan Kattamuri, David M. Luedeke, Xiaodi Deng, Amrita Jagpal, Fuming Zhang, Robert J. Linhardt, Alan P. Kenny, Aaron M. Zorn, Thomas B. Thompson, "Structure of Protein Related to Dan and Cerberus: Insights into the Mechanism of Bone Morphogenetic Protein Antagonism," Structure 21 (8), 1417-1429 (2013). DOI: 10.1016/j.str.2013.06.005

Tengchuan Jin, Mo Huang, Patrick Smith, Jiansheng Jiang, T. Sam Xiao, "Structure of the caspase-recruitment domain from a zebrafish guanylate-binding protein," Acta Crystallogr. F 69 (8), 855-860 (2013). DOI: 10.1107/S1744309113015558

Pedro S. Coelho, Z. Jane Wang, Maraia E. Ener, Stefanie A. Baril, Arvind Kannan, Frances H. Arnold, Eric M. Brustad, "A serine-substituted P450 catalyzes highly efficient carbene transfer to olefins in vivo," Nat. Chem. Biol. 9, 485-487 (2013). DOI: 10.1038/nchembio.1278

Zhiqing Wang, Long Li, Janice G. Pennington, Ju Sheng, Moh Lan Yap, Pavel Plevka, Geng Meng, Lei Sun, Wen Jiang, Michael G. Rossmann, "Obstruction of Dengue Virus Maturation by Fab Fragments of the 2H2 Antibody," J. Virol. 87 (16), 8909-8915 (2013). DOI: 10.1128/JVI.00472-13

Antonio C. Ruzzini, Shiva Bhowmik, Katherine C. Yam, Subhangi Ghosh, Jeffrey T. Bolin, Lindsay D. Eltis, "The Lid Domain of the MCP Hydrolase DxnB2 Contributes to the Reactivity toward Recalcitrant PCB Metabolites," Biochemistry-US 52 (33), 5385-5695 (2013). DOI: 10.1021/bi400774m

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Zachary A. Bornholdt, Takeshi Noda, Dafna M. Abelson, Peter Halfmann, Malcolm R. Wood, Yoshihiro Kawaoka, Erica Ollmann Saphire, "Structural Rearrangement of Ebola Virus VP40 Begets Multiple Functions in the Virus Life Cycle," Cell 154 (4), 763-774 (2013). DOI: 10.1016/j.cell.2013.07.015

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Chris J. Vickers, Gonzalo E. González-Páez, Dennis W. Wolan, "Selective Detection of Caspase-3 versus Caspase-7 Using Activity-Based Probes with Key Unnatural Amino Acids," ACS Chem. Biol. 8 (7), 1558-1566 (2013). DOI: 10.1021/cb400209w

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Egor Svidritskiy, Clarence Ling, Dmitri N. Ermolenko, Andrei A. Korostelev, "Blasticidin S inhibits translation by trapping deformed tRNA on the ribosome," Proc. Natl. Acad. Sci. USA 110 (30), 12283-12288 (2013). DOI: 10.1073/pnas.1304922110

Monika-Sarah E.D. Schulze, Anne-Kathrin Anders, Dhruv K. Sethi, Melissa J. Call, "Disruption of Hydrogen Bonds between Major Histocompatibility Complex Class II and the Peptide NTerminus Is Not Sufficient to Form a Human Leukocyte Antigen-DM Receptive State of Major Histocompatibility Complex Class II," PLoS One 8 (7), e69228-1-e69228-15 (2013). DOI: 10.1371/journal.pone.0069228

Karl R. Schmitz, Atrish Bagchi, Rob C. Roovers, Paul M.P. van Bergen en Henegouwen, Kathryn M. Ferguson, "Structural Evaluation of EGFR Inhibition Mechanisms for Nanobodies/VHH Domains," Structure 21 (7), 1214-1224 (2013). DOI: 10.1016/j.str.2013.05.008

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Erik T. Yukl, Lyndal M.R. Jensen, Victor L. Davidson, Carrie M. Wilmot, "Structures of MauG in complex with quinol and quinone MADH," Acta Crystallogr. F 69 (7), 738-743 (2013). DOI: 10.1107/S1744309113016539

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Tengchuan Jin, James Curry, Patrick Smith, Jiansheng Jiang, T. Sam Xiao, "Structure of the NLRP1 caspase recruitment domain suggests potential mechanisms for its association with procaspase-1," Proteins 81 (7), 1266-1270 (2013). DOI: 10.1002/prot.24287

Bret D. Wallace, Laurie Betts, Garrick Talmage, Rebecca M. Pollet, Natalie S. Holman, Matthew R. Redinbo, "Structural and Functional Analysis of the Human Nuclear Xenobiotic Receptor PXR in Complex with RXR[alpha]," J. Mol. Biol. 425 (14), 2561-2577 (2013). DOI: 10.1016/j.jmb.2013.04.012

Dianfan Li, Syed T.A. Shah, Martin Caffrey, "Host Lipid and Temperature as Important Screening Variables for Crystallizing Integral Membrane Proteins in Lipidic Mesophases. Trials with Diacylglycerol Kinase," Cryst. Growth Des. 13 (7), 2846-2857 (2013). DOI: 10.1021/cg400254v

Pramod Kumar Yadav, Kazuhiro Yamada, Taurai Chiku, Markos Koutmos, Ruma Banerjee, "Structure and Kinetic Analysis of H[subscript 2]S Production by Human Mercaptopyruvate Sulfurtransferase," J. Biol. Chem. 288 (27), 20002-20013 (2013). DOI: 10.1074/jbc.M113.466177

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Kuppan Gokulan, Seán E. O'Leary, William K. Russell, David H. Russell, Mallikarjun Lalgondar, Tadhg P. Begley, Thomas R. Ioerger, James C. Sacchettini, "Crystal Structure of Mycobacterium tuberculosis Polyketide Synthase 11 (PKS11) Reveals Intermediates in the Synthesis of Methyl-branched Alkylpyrones," J. Biol. Chem. 288, 16484-16494 (2013). DOI: 10.1074/jbc.M113.468892

Shilah A. Bonnett, Jonathan R. Whicher, Kancharla Papireddy, Galina Florova, Janet L. Smith, Kevin A. Reynolds, "Structural and Stereochemical Analysis of a Modular Polyketide Synthase Ketoreductase Domain Required for the Generation of a cis-Alkene," Chem. Biol. 20 (6), 772-783 (2013). DOI: 10.1016/j.chembiol.2013.04.014

Jie Zhou, Laura Lancaster, John Paul Donohue, Harry F. Noller, "Crystal Structures of EF-G–Ribosome Complexes Trapped in Intermediate States of Translocation," Science 340, 1236086-1-1236086-7 (2013). DOI: 10.1126/science.1236086

Garry W. Buchko, Jan Abendroth, Howard Robinson, Yanfeng Zhang, Stephen N. Hewitt, Thomas E. Edwards, Wesley C. Van Voorhis, Peter J. Myler, "Crystal structure of a macrophage migration inhibitory factor from Giardia lamblia," J. Struct. Funct. Geno. 14 (2), 47-57 (2013). DOI: 10.1007/s10969-013-9155-9

Feng Wang, Damian C. Ekiert, Insha Ahmad, Wenli Yu, Yong Zhang, Omar Bazirgan, Ali Torkamani, Terje Raudsepp, Waithaka Mwangi, Michael F. Criscitiello, Ian A. Wilson, Peter G. Schultz, Vaughn V. Smider, "Reshaping Antibody Diversity," Cell 153 (6), 1379-1393 (2013). DOI: 10.1016/j.cell.2013.04.049

Sundaresan S. Sigamani, Haiyan Zhao, Yvonne N. Kamau, Joel D. Baines, Liang Tang, "The Structure of the Herpes Simplex Virus DNA-Packaging Terminase pUL15 Nuclease Domain Suggests an Evolutionary Lineage among Eukaryotic and Prokaryotic Viruses," J. Virol. 87 (12), 7140-7148 (2013). DOI: 10.1128/JVI.00311-13

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Ping Liu, Thomas E. Cleveland IV, Samuel Bouyain, Patrick O. Byrne, Patti A. Longo, Daniel J. Leahy, "A single ligand is sufficient to activate EGFR dimers," Proc. Natl. Acad. Sci. USA 109 (27), 10861-10866 (2012). DOI: 10.1073/pnas.1201114109

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Edwin Antony, Elizabeth A. Weiland, Sergey Korolev, Timothy M. Lohman, "Plasmodium falciparum SSB Tetramer Wraps Single-Stranded DNA with Similar Topology but Opposite Polarity to E. coli SSB," J. Mol. Biol. 420 (4-5), 269-283 (2012). DOI: 10.1016/j.jmb.2012.04.021

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Michael A. Hanson, Christopher B. Roth, Euijung Jo, Mark T. Griffith, Fiona L. Scott, Greg Reinhart, Hans Desale, Bryan Clemons, Stuart M. Cahalan, Stephan C. Schuerer, M. Germana Sanna, Gye Won Han, Peter Kuhn, Hugh Rosen, Raymond C. Stevens, "Crystal Structure of a Lipid G Protein–Coupled Receptor," Science 335, 851-855 (2012). DOI: 10.1126/science.1215904

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Jennifer L. Taylor, Rukman S. De Silva, Gabriela Kovacikova, Wei Lin, Ronald K. Taylor, Karen Skorupski, F. Jon Kull, "The crystal structure of AphB, a virulence gene activator from Vibrio cholerae, reveals residues that influence its response to oxygen and pH," Mol. Microbiol. 83 (3), 457-470 (2012). DOI: 10.1111/j.1365-2958.2011.07919.x

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Jennifer J. Gehret, Liangcai Gu, Todd W. Geders, William Clay Brown, Lena Gerwick, William H. Gerwick, David H. Sherman, Janet L. Smith, "Structure and activity of DmmA, a marine haloalkane dehalogenase," Protein Sci. 21 (2), 239-248 (2012). DOI: 10.1002/pro.2009

Christoph Bieniossek, Tsuyoshi Imasaki, Yuichiro Takagi, Imre Berger, "MultiBac: expanding the research toolbox for multiprotein complexes," Trends Biochem. Sci. 37 (2), 49-57 (2012). DOI: 10.1016/j.tibs.2011.10.005

Kazuko Haga, Andrew C. Kruse, Hidetsugu Asada, Takami Yurugi-Kobayashi, Mitsunori Shiroishi, Cheng Zhang, William I. Weis, Tetsuji Okada, Brian K. Kobilka, Tatsuya Haga, Takuya Kobayashi, "Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist," Nature 482, 547-551 (2012). DOI: 10.1038/nature10753

Stephen G. Brohawn, Josefina del Mármol, Roderick MacKinnon, "Crystal Structure of the Human K2P TRAAK, a Lipid- and Mechano-Sensitive K[superscript +] Ion Channel," Science 335, 436-441 (2012). DOI: 10.1126/science.1213808

Shikha Gupta, Martin Gellert, Wei Yang, "Mechanism of mismatch recognition revealed by human MutS[beta] bound to unpaired DNA loops," Nat. Struct. Mol. Biol. 19 (1), 72-78 (2012). DOI: 10.1038/nsmb.2175

Bryan S. Der, Mischa Machius, Michael J. Miley, Jeffrey L. Mills, Thomas Szyperski, Brian Kuhlman, "Metal-Mediated Affinity and Orientation Specificity in a Computationally Designed Protein Homodimer," J. Am. Chem. Soc. 134 (1), 375-385 (2012). DOI: 10.1021/ja208015j

Mona N. Rahman, Jason Z. Vlahakis, Dragic Vukomanovic, Wallace Lee, Walter A. Szarek, Kanji Nakatsu, Zongchao Jia, "A Novel, 'Double-Clamp' Binding Mode for Human Heme Oxygenase-1 Inhibition," PLoS One 7 (1), e29514-1-e29514-11 (2012). DOI: 10.1371/journal.pone.0029514

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Eun Young Yu, Jia Sun, Ming Lei, Neal F. Lue, "Analyses of Candida Cdc13 Orthologues Revealed a Novel OB Fold Dimer Arrangement, Dimerization-Assisted DNA Binding, and Substantial Structural Differences between Cdc13 and RPA70," Mol. Cell Biol. 32 (1), 186-198 (2012). DOI: 10.1128/MCB.05875-11

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Jens Hausmann, Satwik Kamtekar, Evangelos Christodoulou, Jacqueline E. Day, Tao Wu, Zachary Fulkerson, Harald M.H.G. Albers, Laurens A. van Meeteren, Anna J.S. Houben, Leonie van Zeijl, Silvia Jansen, Maria Andries, Troii Hall, Lyle E. Pegg, Timothy E. Benson, Mobien Kasiem, Karl Harlos, Craig W. Vander Kooi, Susan S. Smyth, Huib Ovaa, Mathieu Bollen, Andrew J. Morris, Wouter H. Moolenaar, Anastassis Perrakis, "Structural basis of substrate discrimination and integrin binding by autotaxin," Nat. Struct. Mol. Biol. 18, 198-204 (2011). DOI: 10.1038/nsmb.1980

Hyung Cheol Kim, Alanna M. Steffen, Michael L. Oldham, Jue Chen, Jon M. Huibregtse, "Structure and function of a HECT domain ubiquitin-binding site," EMBO Rep. 12 (4), 334-341 (2011). DOI: 10.1038/embor.2011.23

Melanie A. Adams-Cioaba, Joanne C. Krupa, Chao Xu, John S. Mort, Jinrong Min, "Structural basis for the recognition and cleavage of histone H3 by cathepsin L," Nat. Commun. 2, online (2011). DOI: 10.1038/ncomms1204

Sergey Korolev, "ATP-Binding Cassette Properties of Recombination Mediator Protein RecF," DNA Repair, I. Kruman, eds., Intech, 2011, 431 - 452. DOI: 10.5772/21178

Darren W. Begley, Douglas R. Davies, Robert C. Hartley, Thomas E. Edwards, Bart L. Staker, Wesley C. Van Voorhis, Peter J. Myler, Lance J. Stewart, "Fragment Screening of Infectious Disease Targets in a Structural Genomics Environment," Methods in Enzymology , L.C. Kuo, eds., Elsevier, 2011, 533 - 556. DOI: 10.1016/B978-0-12-381274-2.00021-2

Zunping Liu, Shenglan Xu, Derek W. Yoder, Robert F. Fischetti, "Simulation and optimization of a sub-micron beam for macromolecular crystallography using SHADOW and XOP at GM/CA CAT at the APS," R.J. Koshel, G.G. Gregory, Novel Optical Systems Design and Optimization XIV, eds., 8129, SPIE (2011), 81290E-1 - 81290E-8. DOI: 10.1117/12.894173

Shu-Xing Li, Sun Huang, Nina Bren, Kaori Noridomi, Cosma D. Dellisanti, Steven M. Sine, Lin Chen, "Ligand-binding domain of an [alpha subscript 7]-nicotinic receptor chimera and its complex with agonist," Nat. Neurosci. 14, 1253-1259 (2011). DOI: 10.1038/nn.2908

Peder Cedervall, "Victor A. Bloomfield Fellowship," (2011).

Brandon Goblirsch, "Pauling Poster Prize," (2011).

Darya V. Urusova, Jung-Hyun Shim, Dong Joon Kim, Sung Keun Jung, Tatyana A. Zykova, Andria Carper, Ann M. Bode, Zigang Dong, "Epigallocatechin-gallate Suppresses Tumorigenesis by Directly Targeting Pin1," Cancer Prev. Res. 4, 1366-1377 (2011). DOI: 10.1158/1940-6207.CAPR-11-0301

Ju He, Jun Ye, Yongfei Cai, Cecilia Riquelme, Jun O. Liu, Xuedong Liu, Aidong Han, Lin Chen, "Structure of p300 bound to MEF2 on DNA reveals a mechanism of enhanceosome assembly," Nucleic Acids Res. 39 (10), 4464-4474 (2011). DOI: 10.1093/nar/gkr030

Anastasia A. Aksyuk, Lidia P. Kurochkina, Andrei Fokine, Farhad Forouhar, Vadim V. Mesyanzhinov, Liang Tong, Michael G. Rossmann, "Structural Conservation of the Myoviridae Phage Tail Sheath Protein Fold," Structure 19 (12), 1885-1894 (2011). DOI: 10.1016/j.str.2011.09.012

Ismael Alicea, Jonathan S. Marvin, Aleksandr E. Miklos, Andrew D. Ellington, Loren L. Looger, Eric R. Schreiter, "Structure of the Escherichia coli Phosphonate Binding Protein PhnD and Rationally Optimized Phosphonate Biosensors," J. Mol. Biol. 414 (3), 356-369 (2011). DOI: 10.1016/j.jmb.2011.09.047

Jason S. McLellan, Marie Pancera, Chris Carrico, Jason Gorman, Jean-Philippe Julien, Reza Khayat, Robert Louder, Robert Pejchal, Mallika Sastry, Kaifan Dai, Sijy O’Dell, Nikita Patel, Syed Shahzad-ul-Hussan, Yongping Yang, Baoshan Zhang, Tongqing Zhou, Jiang Zhu, Jeffrey C. Boyington, Gwo-Yu Chuang, Devan Diwanji, Ivelin Georgiev, Young Do Kwon, Doyung Lee, Mark K. Louder, Stephanie Moquin, Stephen D. Schmidt, Zhi-Yong Yang, Mattia Bonsignori, John A. Crump, Saidi H. Kapiga, Noel E. Sam, Barton F. Haynes, Dennis R. Burton, Wayne C. Koff, Laura M. Walker, Sanjay Phogat, Richard Wyatt, Jared Orwenyo, Lai-Xi Wang, James Arthos, Carole A. Bewley, John R. Mascola, Gary J. Nabel, William R. Schief, Andrew B. Ward, Ian A. Wilson, Peter D. Kwong, "Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9," Nature 480, 336-343 (2011). DOI: 10.1038/nature10696

Vladimir Yu. Torbeev, H. Raghuraman, Donald Hamelberg, Marco Tonelli, William M. Westler, Eduardo Perozo, Stephen B.H. Kent, "Protein conformational dynamics in the mechanism of HIV-1 protease catalysis," Proc. Natl. Acad. Sci. USA 108 (52), 20982-20987 (2011). DOI: 10.1073/pnas.1111202108

Mary Khanna, Che-Hong Chen, Ann Kimble-Hill, Bibek Parajuli, Samantha Perez-Miller, Sulochanadevi Baskaran, Jeewon Kim, Karl Dria, Vasilis Vasiliou, Daria Mochly-Rosen, Thomas D. Hurley, "Discovery of a novel class of covalent inhibitor for aldehyde dehydrogenases," J. Biol. Chem. 286 (50), 43486-43494 (2011). DOI: 10.1074/jbc.M111.293597

Tomoyasu Ishikawa, Masaki Seto, Hiroshi Banno, Youichi Kawakita, Mami Oorui, Takahiko Taniguchi, Yoshikazu Ohta, Toshiya Tamura, Akiko Nakayama, Hiroshi Miki, Hidenori Kamiguchi, Toshimasa Tanaka, Noriyuki Habuka, Satoshi Sogabe, Jason Yano, Kathleen Aertgeerts, Keiji Kamiyama, "Design and Synthesis of Novel Human Epidermal Growth Factor Receptor 2 (HER2)/Epidermal Growth Factor Receptor (EGFR) Dual Inhibitors Bearing a Pyrrolo[3,2-d]pyrimidine Scaffold," J. Med. Chem. 54 (23), 8030-8050 (2011). DOI: 10.1021/jm2008634

P. Benjamin Stranges, Mischa Machius, Michael J. Miley, Ashutosh Tripathy, Brian Kuhlman, "Computational design of a symmetric homodimer using [beta]-strand assembly," Proc. Natl. Acad. Sci. USA 108 (51), 20562-20567 (2011). DOI: 10.1073/pnas.1115124108

Robyn L. Stanfield, Jean-Philippe Julien, Robert Pejchal, Johannes S. Gach, Michael B. Zwick, Ian A. Wilson, "Structure-Based Design of a Protein Immunogen that Displays an HIV-1 gp41 Neutralizing Epitope," J. Mol. Biol. 414 (3), 460-476 (2011). DOI: 10.1016/j.jmb.2011.10.014

Tushar K. Maiti, Michelle Permaul, David A. Boudreaux, Christina Mahanic, Sarah Mauney, Chittaranjan Das, "Crystal structure of the catalytic domain of UCHL5, a proteasome-associated human deubiquitinating enzyme, reveals an unproductive form of the enzyme," FEBS J. 278 (24), 4917-4926 (2011). DOI: 10.1111/j.1742-4658.2011.08393.x

Nadine L. Samara, Cynthia Wolberger, "A new chapter in the transcription SAGA," Curr. Opin. Struct. Biol. 21 (6), 767-774 (2011). DOI: 10.1016/j.sbi.2011.09.004

Byung Woo Han, Thomas E. Malone, Do Jin Kim, Craig A. Bingman, Hyun-Jung Kim, Brian G. Fox, George N. Phillips Jr., "Crystal structure of Arabidopsis thaliana 12-oxophytodienoate reductase isoform 3 in complex with 8-iso prostaglandin A[subscript 1]," Proteins 79 (11), 3236-3241 (2011). DOI: 10.1002/prot.23153

Srinivas Somarowthu, Heather R. Brodkin, J. Alejandro D’Aquino, Dagmar Ringe, Mary Jo Ondrechen, Penny J. Beuning, "A Tale of Two Isomerases: Compact versus Extended Active Sites in Ketosteroid Isomerase and Phosphoglucose Isomerase," Biochemistry-US 50 (43), 9283-9295 (2011). DOI: 10.1021/bi201089v

Karl E. Zahn, April Averill, Susan S. Wallace, Sylvie Doublié, "The Miscoding Potential of 5-Hydroxycytosine Arises Due to Template Instability in the Replicative Polymerase Active Site," Biochemistry-US 50 (47), 10350-10358 (2011). DOI: 10.1021/bi201219s

Ce Shi, Todd W. Geders, Sae Woong Park, Daniel J. Wilson, Helena I. Boshoff, Orishadipe Abayomi, Clifton E. Barry, III, Dirk Schnappinger, Barry C. Finzel, Courtney C. Aldrich, "Mechanism-based Inactivation by Aromatization of the Transaminase BioA Involved in Biotin Biosynthesis in Mycobaterium tuberculosis," J. Am. Chem. Soc. 133 (45), 18194-18201 (2011). DOI: 10.1021/ja204036t

Robert Pejchal, Katie J. Doores, Laura M. Walker, Reza Khayat, Po-Ssu Huang, Sheng-Kai Wang, Robyn L. Stanfield, Jean-Philippe Julien, Alejandra Ramos, Max Crispin, Rafael Depetris, Umesh Katpally, Andre Marozsan, Albert Cupo, Sebastien Maloveste, Yan Liu, Ryan McBride, Yukishige Ito, Rogier W. Sanders, Cassandra Ogohara, James C. Paulson, Ten Feizi, Christopher N. Scanlan, Chi-Huey Wong, John P. Moore, William C. Olson, Andrew B. Ward, Pascal Poignard, William R. Schief, Dennis R. Burton, Ian A. Wilson, "A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield," Science 334, 1097-1103 (2011). DOI: 10.1126/science.1213256

Stephen M. Smith, Swati Rawat, Joshua Telser, Brian M. Hoffman, Timothy L. Stemmler, Amy C. Rosenzweig, "Crystal Structure and Characterization of Particulate Methane Monooxygenase from Methylocystis species Strain M," Biochemistry-US 50 (47), 10231-10240 (2011). DOI: 10.1021/bi200801z

Shu-Mei He, Matthew Wathier, Kateryna Podzelinska, Matthew Wong, Fern R. McSorley, Alemayehu Asfaw, Bjarne Hove-Jensen, Zongchao Jia, David L. Zechel, "Structure and Mechanism of PhnP, a Phosphodiesterase of the Carbon-Phosphorus Lyase Pathway," Biochemistry-US 50 (40), 8603-8615 (2011). DOI: 10.1021/bi2005398

Claudiu M. Nelersa, Brad J. Schmier, Arun Malhotra, "Purification and crystallization of Bacillus subtilis NrnA, a novel enzyme involved in nanoRNA degradation," Acta Crystallogr. F 67 (10), 1235-1238 (2011). DOI: 10.1107/S1744309111026509

Chun-Chi Lin, Kyuwon Baek, Zhe Lu, "Apo and InsP[subscript 3]-bound crystal structures of the ligand-binding domain of an InsP[subscript 3] receptor," Nat. Struct. Mol. Biol. 18 (10), 1172-1174 (2011). DOI: 10.1038/nsmb.2112

Brian Bae, Ryan E. Cobb, Matthew A. DeSieno, Huimin Zhao, Satish K. Nair, "New N-Acetyltransferase Fold in the Structure and Mechanism of the Phosphonate Biosynthetic Enzyme FrbF," J. Biol. Chem. 286 (41), 36132-36141 (2011). DOI: 10.1074/jbc.M111.263533

Christopher W. Davies, Lake N. Paul, Myung-Il Kim, Chittaranjan Das, "Structural and Thermodynamic Comparison of the Catalytic Domain of AMSH and AMSH-LP: Nearly Identical Fold but Different Stability," J. Mol. Biol. 413 (2), 416-429 (2011). DOI: 10.1016/j.jmb.2011.08.029

Aram Chang, Shanteri Singh, Kate E. Helmich, Randal D. Goff, Craig A. Bingman, Jon S. Thorson, George N. Phillips, Jr., "Complete set of glycosyltransferase structures in the calicheamicin biosynthetic pathway reveals the origin of regiospecificity," Proc. Natl. Acad. Sci. USA 108 (43), 17649-17654 (2011). DOI: 10.1073/pnas.1108484108

Nafez Abu Tarboush, Lyndal M.R. Jensen, Erik T. Yukl, Jiafeng Geng, Aimin Liu, Carrie M. Wilmot, Victor L. Davidson, "Mutagenesis of tryptophan199 suggests that hopping is required for MauG-dependent tryptophan tryptophylquinone biosynthesis," Proc. Natl. Acad. Sci. USA 108 (41), 16956-16961 (2011). DOI: 10.1073/pnas.1109423108

David B. Sauer, Weizhong Zeng, Srinivasan Raghunathan, Youxing Jiang, "Protein interactions central to stabilizing the K[superscript +] channel selectivity filter in a four-sited configuration for selective K[superscript +] permeation," Proc. Natl. Acad. Sci. USA 108 (40), 16634-16639 (2011). DOI: 10.1073/pnas.1111688108

S. Xu, V. Nagarajan, R.F. Fischetti, "Design and manufacture of mini-beam collimators for macromolecular crystallography at the GM/CA-CAT at APS," Diamond Light Source Proceedings, MEDSI-6 , Diamond Light Source, (2011), e27-1 - e27-4. DOI: 10.1017/S2044820110000353

Paola Sette, Ruiling Mu, Vincent Dussupt, Jiansheng Jiang, Greg Snyder, Patrick Smith, Tsan Sam Xiao, Fadila Bouamr, "The Phe105 Loop of Alix Bro1 Domain Plays a Key Role in HIV-1 Release," Structure 19 (10), 1485-1495 (2011). DOI: 10.1016/j.str.2011.07.016

David L. Akey, Shengying Li, Jamie R. Konwerski, Laura A. Confer, Steffen M. Bernard, Yojiro Anzai, Fumio Kato, David H. Sherman, Janet L. Smith, "A New Structural Form in the SAM/Metal-Dependent O‑Methyltransferase Family: MycE from the Mycinamicin Biosynthetic Pathway," J. Mol. Biol. 413 (2), 438-450 (2011). DOI: 10.1016/j.jmb.2011.08.040

Kimihisa Yoshida, Hyuk-Soo Seo, Erik W. Debler, Günter Blobel, André Hoelz, "Structural and functional analysis of an essential nucleoporin heterotrimer on the cytoplasmic face of the nuclear pore complex," Proc. Natl. Acad. Sci. USA 108 (40), 16571-16576 (2011). DOI: 10.1073/pnas.1112846108

Shenglan Xu, Lisa J. Keefe, Anne Mulichak, Lifen Yan, Ercan E. Alp, Jiyong Zhao, Robert F. Fischetti, "Mini-beam collimator applications at the Advanced Photon Source," Nucl. Instrum. Methods A 649 (1), 104-106 (2011). DOI: 10.1016/j.nima.2010.11.008

Darren W. Begley, Douglas R. Davies, Robert C. Hartley, Stephen N. Hewitt, Amanda L. Rychel, Peter J. Myler, Wesley C. Van Voorhis, Bart L. Staker, Lance J. Stewart, "Probing conformational states of glutaryl-CoA dehydrogenase by fragment screening," Acta Crystallogr. F 67 (9), 1060-1069 (2011). DOI: 10.1107/S1744309111014436

Pierre Aller, Stéphanie Duclos, Susan S. Wallace, Sylvie Doublié, "A Crystallographic Study of the Role of Sequence Context in Thymine Glycol Bypass by a Replicative DNA Polymerase Serendipitously Sheds Light on the Exonuclease Complex," J. Mol. Biol. 412 (1), 22-34 (2011). DOI: 10.1016/j.jmb.2011.07.007

O. Makarov, M. Hilgart, C. Ogata, S. Pothineni, C. Cork, "Control system for the 2nd generation Berkeley automounters (BAM2) at GM/CA-CAT macromolecular crystallography beamlines," Nucl. Instrum. Methods A 649 (1), 87-90 (2011). DOI: 10.1016/j.nima.2010.12.244

Douglas R. Davies, Bart L. Staker, Jan A. Abendroth, Thomas E. Edwards, Robert Hartley, Jess Leonard, Hidong Kim, Amanda L. Rychel, Stephen N. Hewitt, Peter J. Myler, Lance J. Stewart, "An ensemble of structures of Burkholderia pseudomallei 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase," Acta Crystallogr. F 67 (9), 1044-1050 (2011). DOI: 10.1107/S1744309111030405

Søren G.F. Rasmussen, Brian T. DeVree, Yaozhong Zou, Andrew C. Kruse, Ka Young Chung, Tong Sun Kobilka, Foon Sun Thian, Pil Seok Chae, Els Pardon, Diane Calinski, Jesper M. Mathiesen, Syed T.A. Shah, Joseph A. Lyons, Martin Caffrey, Samuel H. Gellman, Jan Steyaert, Georgios Skiniotis, William I. Weis, Roger K. Sunahara, Brian K. Kobilka, "Crystal structure of the [beta subscript 2] adrenergic receptor–Gs protein complex," Nature 477, 549-555 (2011). DOI: 10.1038/nature10361

L.E. Berman, M. Allaire, M.R. Chance, W.A. Hendrickson, A. Héroux, J. Jakoncic, Q. Liu, A.M. Orville, H.H. Robinson, D.K. Schneider, W. Shi, A.S. Soares, V. Stojanoff, D. Stoner-Ma, R.M. Sweet, "Opticsconcept for apair of undulatorbeamlines for MX," Nucl. Instrum. Methods A 649 (1), 131-135 (2011). DOI: 10.1016/j.nima.2010.12.030

Mark C. Hilgart, Ruslan Sanishvili, Craig M. Ogata, Michael Becker, Nagarajan Venugopalan, Sergey Stepanov, Oleg Makarov, Janet L. Smith, Robert F. Fischetti, "Automated sample-scanning methods for radiation damage mitigation and diffraction-based centering of macromolecular crystals," J. Synchrotron Rad. 18 (5), 717-722 (2011). DOI: 10.1107/S0909049511029918

S. Xu, V. Nagarajan, R. Sanishvili, R.F. Fischetti, "Alignment protocol for effective use of hard x-ray quad collimator for micro-crystallography," Optomechanics 2011: Innovations and Solutions, A.E. Hatheway, eds., 8125, SPIE, (2011), 81250X-1 - 81250X-8. DOI: 10.1117/12.894262

Derek W. Yoder, Oleg Makarov, Stephen Corcoran, Robert F. Fischetti, "PID feedback control of monochromator thermal stabilization," Nucl. Instrum. Methods A 649 (1), 107-108 (2011). DOI: 10.1016/j.nima.2010.11.177

Matthew R. Whorton, Roderick MacKinnon, "Crystal Structure of the Mammalian GIRK2 K[superscript +] Channel and Gating Regulation by G Proteins, PIP[subscript 2], and Sodium," Cell 147 (1), 199-208 (2011). DOI: 10.1016/j.cell.2011.07.046

Sulochanadevi Baskaran, Vimbai M. Chikwana, Christopher J. Contreras, Keri D. Davis, Wayne A. Wilson, Anna A. DePaoli-Roach, Peter J. Roach, Thomas D. Hurley, "Multiple Glycogen-binding Sites in Eukaryotic Glycogen Synthase Are Required for High Catalytic Efficiency toward Glycogen," J. Biol. Chem. 286 (39), 33999-34006 (2011). DOI: 10.1074/jbc.M111.264531

Michael L. Oldham, Jue Chen, "Snapshots of the maltose transporter during ATP hydrolysis," Proc. Natl. Acad. Sci. USA 108 (37), 15152-15156 (2011). DOI: 10.1073/pnas.1108858108

Hiroyuki Tanaka, Miki Senda, Nagarajan Venugopalan, Atsushi Yamamoto, Toshiya Senda, Tetsuo Ishida, Kihachiro Horiike, "Crystal Structure of a Zinc-dependent d-Serine Dehydratase from Chicken Kidney," J. Biol. Chem. 286 (31), 27548-27558 (2011). DOI: 10.1074/jbc.M110.201160

Sergey Stepanov, Mark Hilgart, Derek W. Yoder, Oleg Makarov, Michael Becker, Ruslan Sanishvili, Craig M. Ogata, Nagarajan Venugopalan, David Aragão, Martin Caffrey, Janet L. Smith, Robert F. Fischetti, "Fast fluorescence techniques for crystallography beamlines," J. Appl. Crystallogr. 44 (4), 772-778 (2011). DOI: 10.1107/S0021889811016748

Lee Makowski, David Gore, Suneeta Mandava, David Minh, Sanghyun Park, Diane J. Rodi, Robert F. Fischetti, "X-ray solution scattering studies of the structural diversity intrinsic to protein ensembles," Biopolymers 95 (8), 531-542 (2011). DOI: 10.1002/bip.21631

Andrei Fokine, Mohammad Z. Islam, Zhihong Zhang, Valorie D. Bowman, Venigalla B. Rao, Michael G. Rossmann, "Structure of the Three N-Terminal Immunoglobulin Domains of the Highly Immunogenic Outer Capsid Protein from a T4-Like Bacteriophage," J. Virol. 85 (16), 8141-8148 (2011). DOI: 10.1128/JVI.00847-11

Ning Shi, Weizhong Zeng, Sheng Ye, Yang Li, Youxing Jiang, "Crucial Points within the Pore as Determinants of K[superscript +] Channel Conductance and Gating," J. Mol. Biol. 411 (1), 27-35 (2011). DOI: 10.1016/j.jmb.2011.04.058

Reza Khayat, Nicholas Brunn, Jeffrey A. Speir, John M. Hardham, Robert G. Ankenbauer, Anette Schneemann, John E. Johnson, "The 2.3-Angstrom Structure of Porcine Circovirus 2," J. Virol. 85 (15), 7856-7862 (2011). DOI: 10.1128/JVI.00737-11

Monica Ilies, Luigi Di Costanzo, Daniel P. Dowling, Katherine J. Thorn, David W. Christianson, "Binding of [alpha, alpha]-Disubstituted Amino Acids to Arginase Suggests New Avenues for Inhibitor Design," J. Med. Chem. 54 (15), 5432-5443 (2011). DOI: 10.1021/jm200443b

Jennifer Bridwell-Rabb, Andrew M. Winn, David P. Barondeau, "Structure–Function Analysis of Friedreich’s Ataxia Mutants Reveals Determinants of Frataxin Binding and Activation of the Fe–S Assembly Complex," Biochemistry-US 50 (33), 7265-7274 (2011). DOI: 10.1021/bi200895k

Sung-il Yoon, Minsun Hong, Ian A Wilson, "An unusual dimeric structure and assembly for TLR4 regulator RP105–MD-1," Nat. Struct. Mol. Biol. 18, 1028-1035 (2011). DOI: 10.1038/nsmb.2106

Johanne Le Coq, Partho Ghosh, "Conservation of the C-type lectin fold for massive sequence variation in a Treponema diversity-generating retroelement," Proc. Natl. Acad. Sci. USA 108 (35), 14649-14652 (2011). DOI: 10.1073/pnas.1105613108

Markos Koutmos, Carmen Gherasim, Janet L. Smith, Ruma Banerjee, "Structural Basis of Multifunctionality in a Vitamin B[subscript 12]-processing Enzyme," J. Biol. Chem. 286 (34), 29780-29787 (2011). DOI: 10.1074/jbc.M111.261370

Pedro Brugarolas, Erica M. Duguid, Wen Zhang, Catherine B. Poor, Chuan He, "Structural and biochemical characterization of N[superscript 5]-carboxyaminoimidazole ribonucleotide synthetase and N[superscript 5]-carboxyaminoimidazole ribonucleotide mutase from Staphylococcus aureus," Acta Crystallogr. D 67 (8), 707-715 (2011). DOI: 10.1107/S0907444911023821

Tsuyoshi Imasaki, Guillermo Calero, Gang Cai, Kuang-Lei Tsai, Kentaro Yamada, Francesco Cardelli, Hediye Erdjument-Bromage, Paul Tempst, Imre Berger, Guy Lorch Kornberg, Francisco J. Asturias, Roger D. Kornberg, Yuichiro Takagi, "Architecture of the Mediator head module," Nature 475, 240-243 (2011). DOI: 10.1038/nature10162

Nataliya Nady, Alexander Lemak, John R. Walker, George V. Avvakumov, Michael S. Kareta, Mayada Achour, Sheng Xue, Shili Duan, Abdellah Allali-Hassani, Xiaobing Zuo, Yun-Xing Wang, Christian Bronner, Frédéric Chédin, Cheryl H. Arrowsmith, Sirano Dhe-Paganon, "Recognition of Multivalent Histone States Associated with Heterochromatin by UHRF1 Protein," J. Biol. Chem. 286 (27), 24300-24311 (2011). DOI: 10.1074/jbc.M111.234104

Jinjin Zhang, Kimberly A. McCabe, Charles E. Bell, "Crystal structures of [lamda] exonuclease in complex with DNA suggest an electrostatic ratchet mechanism for processivity," Proc. Natl. Acad. Sci. USA 108 (29), 11872-11877 (2011). DOI: 10.1073/pnas.1103467108

Chi-Lin Tsai, Jennifer Bridwell-Rabb, David P. Barondeau, "Friedreich’s Ataxia Variants I154F and W155R Diminish Frataxin-Based Activation of the Iron–Sulfur Cluster Assembly Complex," Biochemistry-US 50 (29), 6478-6487 (2011). DOI: 10.1021/bi200666h

Shanteri Singh, Aram Chang, Randal D. Goff, Craig A. Bingman, Sabine Grüschow, David H. Sherman, George N. Phillips, Jr., Jon S. Thorson, "Structural characterization of the mitomycin 7-O-methyltransferase," Proteins 79 (7), 2181-2188 (2011). DOI: 10.1002/prot.23040

Karl E. Zahn, Egor P. Tchesnokov, Matthias Götte, Sylvie Doublié, "Phosphonoformic Acid Inhibits Viral Replication by Trapping the Closed Form of the DNA Polymerase," J. Biol. Chem. 286 (28), 25246-25255 (2011). DOI: 10.1074/jbc.M111.248864

Xin Liu, David A. Bushnell, Daniel-Adriano Silva, Xuhui Huang, Roger D. Kornberg, "Initiation Complex Structure and Promoter Proofreading," Science 33, 633-637 (2011). DOI: 10.1126/science.1206629

Theresa Tiefenbrunn, Wei Liu, Ying Chen, Vsevolod Katritch, C. David Stout, James A. Fee, Vadim Cherezov, "High Resolution Structure of the ba3 Cytochrome c Oxidase from Thermus thermophilus in a Lipidic Environment," PLoS One 6 (7), e22348-1-e22348-12 (2011). DOI: 10.1371/journal.pone.0022348

Qingping Xu, Neil D. Rawlings, Hsiu-Ju Chiu, Lukasz Jaroszewski, Heath E. Klock, Mark W. Knuth, Mitchell D. Miller, Marc-Andre Elsliger, Ashley M. Deacon, Adam Godzik, Scott A. Lesley, Ian A. Wilson, "Structural Analysis of Papain-Like NlpC/P60 Superfamily Enzymes with a Circularly Permuted Topology Reveals Potential Lipid Binding Sites," PLoS One 6 (7), e22013-1-e22013-10 (2011). DOI: 10.1371/journal.pone.0022013

Janesh Kumar, Peter Schuck, Mark L. Mayer, "Structure and Assembly Mechanism for Heteromeric Kainate Receptors," Neuron 71 (2), 319-331 (2011). DOI: 10.1016/j.neuron.2011.05.038

Nicholas Noinaj, Mary A. Bosserman, M. Alexandra Schickli, Grzegorz Piszczek, Madan K. Kharel, Pallab Pahari, Susan K. Buchanan, Jürgen Rohr, "The Crystal Structure and Mechanism of an Unusual Oxidoreductase, GilR, Involved in Gilvocarcin V Biosynthesis," J. Biol. Chem. 286 (26), 23533-23543 (2011). DOI: 10.1074/jbc.M111.247833

Serdar Uysal, Luis G. Cuello, D. Marien Cortes, Shohei Koide, Anthony A. Kossiakoff, Eduardo Perozo, "Mechanism of activation gating in the full-length KcsA K[superscript +] channel," Proc. Natl. Acad. Sci. USA 108 (29), 11896-11899 (2011). DOI: 10.1073/pnas.1105112108

Kunio S. Misono, John S. Philo, Tsutomu Arakawa, Craig M. Ogata, Yue Qiu, Haruo Ogawa, Howard S. Young, "Structure, signaling mechanism and regulation of the natriuretic peptide receptor guanylate cyclase," FEBS J. 278 (11), 1818-1829 (2011). DOI: 10.1111/j.1742-4658.2011.08083.x

Natallia Strushkevich, Farrell MacKenzie, Tatyana Cherkesova, Irina Grabovec, Sergey Usanov, Hee-Won Park, "Structural basis for pregnenolone biosynthesis by the mitochondrial monooxygenase system," Proc. Natl. Acad. Sci. USA 108 (25), 10139-10143 (2011). DOI: 10.1073/pnas.1019441108

Kyle T. Dolan, Erica M. Duguid, Chuan He, "Crystal Structures of SlyA Protein, a Master Virulence Regulator of Salmonella, in Free and DNA-bound States," J. Biol. Chem. 286 (25), 22178-22185 (2011). DOI: 10.1074/jbc.M111.245258

Minlong Shi, Jianghai Zhu, Rui Wang, Xing Chen, Lizhi Mi, Thomas Walz, Timothy A. Springer, "Latent TGF-[beta] structure and activation," Nature 474, 343-349 (2011). DOI: 10.1038/nature10152

Michael L. Oldham, Jue Chen, "Crystal Structure of the Maltose Transporter in a Pretranslocation Intermediate State," Science 332, 1202-1205 (2011). DOI: 10.1126/science.1200767

Heather R. Brodkin, Walter R.P. Novak, Amy C. Milne, J. Alejandro D’Aquino, N.M. Karabacak, Ilana G. Goldberg, Jeffrey N. Agar, Mark S. Payne, Gregory A. Petsko, Mary Jo Ondrechen, Dagmar Ringe, "Evidence of the Participation of Remote Residues in the Catalytic Activity of Co-Type Nitrile Hydratase from Pseudomonas putida," Biochemistry-US 50 (22), 4923-4935 (2011). DOI: 10.1021/bi101761e

Jiusheng Lin, Mark A. Wilson, "Escherichia coli Thioredoxin-like Protein YbbN Contains an Atypical Tetratricopeptide Repeat Motif and Is a Negative Regulator of GroEL," J. Biol. Chem. 286 (22), 19459-19469 (2011). DOI: 10.1074/jbc.M111.238741

Pavel Plevka, Bärbel Kaufmann, Michael G. Rossmann, "Analysis of phases in the structure determination of an icosahedral virus," Acta Crystallogr. D 67 (6), 568-577 (2011). DOI: 10.1107/S090744491101448X

Jonathan R. Whicher, Galina Florova, Paulina K. Sydor, Renu Singh, Mamoun Alhamadsheh, Gregory L. Challis, Kevin A. Reynolds, Janet L. Smith, "Structure and Function of the RedJ Protein, a Thioesterase from the Prodiginine Biosynthetic Pathway in Streptomyces coelicolor," J. Biol. Chem. 286 (25), 22558-22569 (2011). DOI: 10.1074/jbc.M110.213512

Amie K. Boal, Tyler L. Grove, Monica I. McLaughlin, Neela H. Yennawar, Squire J. Booker, Amy C. Rosenzweig, "Structural Basis for Methyl Transfer by a Radical SAM Enzyme," Science 332, 1089-1092 (2011). DOI: 10.1126/science.1205358

Qun Wan, Md Faiz Ahmad, James Fairman, Bonnie Gorzelle, María de la Fuente, Chris Dealwis, Michael E. Maguire, "X-Ray Crystallography and Isothermal Titration Calorimetry Studies of the Salmonella Zinc Transporter ZntB," Structure 19 (5), 700-710 (2011). DOI: 10.1016/j.str.2011.02.011

Arulandu Arockiasamy, Anup Aggarwal, Christos G. Savva, Andreas Holzenburg, James C. Sacchettini, "Crystal structure of calcium dodecin (Rv0379), from Mycobacterium tuberculosis with a unique calcium-binding site," Protein Sci. 20 (5), 827-833 (2011). DOI: 10.1002/pro.607

L. Makowski, J. Bardhan, D. Gore, J. Lal, S. Mandava, S. Park, D.J. Rodi, N.T. Ho, C. Ho, R.F. Fischetti, "WAXS Studies of the Structural Diversity of Hemoglobin in Solution," J. Mol. Biol. 408 (5), 909-921 (2011). DOI: 10.1016/j.jmb.2011.02.062

Robert N. Kirchdoerfer, Amanda L. Garner, Caralyn E. Flack, Jenny M. Mee, Alexander R. Horswill, Kim D. Janda, Gunnar F. Kaufmann, Ian A. Wilson, "Structural Basis for Ligand Recognition and Discrimination of a Quorum-quenching Antibody," J. Biol. Chem. 286 (19), 17351-17358 (2011). DOI: 10.1074/jbc.M111.231258

Louis M. Lazar, S. Zoe Fisher, Aaron G. Moulin, Andrey Kovalevsky, Walter R.P. Novak, Paul Langan, Gregory A. Petsko, Dagmar Ringe, "Time-of-flight neutron diffraction study of bovine [gamma]-chymotrypsin at the Protein Crystallography Station," Acta Crystallogr. F 67 (5), 587-590 (2011). DOI: 10.1107/S1744309111009341

Wenjun Cui, Jingzhi Li, David Ron, Bingdong Sha, "The structure of the PERK kinase domain suggests the mechanism for its activation," Acta Crystallogr. D 67 (5), 423-428 (2011). DOI: 10.1107/S0907444911006445

Alexei S. Soares, Matthew A. Engel, Richard Stearns, Sammy Datwani, Joe Olechno, Richard Ellson, John M. Skinner, Marc Allaire, Allen M. Orville, "Acoustically Mounted Microcrystals Yield High-Resolution X-ray Structures," Biochemistry-US 50 (21), 4399-4401 (2011). DOI: 10.1021/bi200549x

Sarel J. Fleishman, Timothy A. Whitehead, Damian C. Ekiert, Cyrille Dreyfus, Jacob E. Corn, Eva-Maria Strauch, Ian A. Wilson, David Baker, "Computational Design of Proteins Targeting the Conserved Stem Region of Influenza Hemagglutinin," Science 332, 816-821 (2011). DOI: 10.1126/science.1202617

Rui Xu, Ian A. Wilson, "Structural Characterization of an Early Fusion Intermediate of Influenza Virus Hemagglutinin," J. Virol. 85 (10), 5172-5182 (2011). DOI: 10.1128/JVI.02430-10

Bärbel Kaufmann, Mohamed El-Far, Pavel Plevka, Valorie D. Bowman, Yi Li, Peter Tijssen, Michael G. Rossmann, "Structure of Bombyx mori Densovirus 1, a Silkworm Pathogen," J. Virol. 85 (10), 4691-4697 (2011). DOI: 10.1128/JVI.02688-10

Brett Spurrier, Jared M. Sampson, Maxim Totrov, Huiguang Li, Timothy O'Neal, Constance Williams, James Robinson, Miroslaw K. Gorny, Susan Zolla-Pazner, Xiang-Peng Kong, "Structural Analysis of Human and Macaque mAbs 2909 and 2.5B: Implications for the Configuration of the Quaternary Neutralizing Epitope of HIV-1 gp120," Structure 19 (5), 691-699 (2011). DOI: 10.1016/j.str.2011.02.012

Narayanan Veeraraghavan, Abir Ganguly, Jui-Hui Chen, Philip C. Bevilacqua, Sharon Hammes-Schiffer, Barbara L. Golden, "Metal Binding Motif in the Active Site of the HDV Ribozyme Binds Divalent and Monovalent Ions," Biochemistry-US 50 (13), 2672-2682 (2011). DOI: 10.1021/bi2000164

Chen Chen, Natalia Gorlatova, Zvi Kelman, Osnat Herzberg, "Structures of p63 DNA binding domain in complexes with half-site and with spacer-containing full response elements," Proc. Natl. Acad. Sci. USA 108 (16), 6456-6461 (2011). DOI: 10.1073/pnas.1013657108

Gira Bhabha, Jeeyeon Lee, Damian C. Ekiert, Jongsik Gam, Ian A. Wilson, H. Jane Dyson, Stephen J. Benkovic, Peter E. Wright, "A Dynamic Knockout Reveals That Conformational Fluctuations Influence the Chemical Step of Enzyme Catalysis," Science 332, 234-238 (2011). DOI: 10.1126/science.1198542

Pauline Macheboeuf, Cosmo Buffalo, Chi-yu Fu, Annelies S. Zinkernagel, Jason N. Cole, John E. Johnson, Victor Nizet, Partho Ghosh, "Streptococcal M1 protein constructs a pathological host fibrinogen network," Nature 472, 64-68 (2011). DOI: 10.1038/nature09967

Fei Xu, Huixian Wu, Vsevolod Katritch, Gye Won Han, Kenneth A. Jacobson, Zhan-Guo Gao, Vadim Cherezov, Raymond C. Stevens, "Structure of an Agonist-Bound Human A[subscript 2A] Adenosine Receptor," Science 332, 322-327 (2011). DOI: 10.1126/science.1202793

E. Sethe Burgie, Craig A. Bingman, Shin-ichi Makino, Gary E. Wesenberg, Xiaokang Pan, Brian G. Fox, George N. Phillips, Jr., "Structural architecture of Galdieria sulphuraria DCN1L," Proteins 79 (4), 1329-1336 (2011). DOI: 10.1002/prot.22937

Erik T. Yukl, Brandon R. Goblirsch, Victor L. Davidson, Carrie M. Wilmot, "Crystal Structures of CO and NO Adducts of MauG in Complex with Pre-Methylamine Dehydrogenase: Implications for the Mechanism of Dioxygen Activation," Biochemistry-US 50 (14), 2931-2938 (2011). DOI: 10.1021/bi200023n

Nicole Hfer, David Aragao, Joseph A. Lyons, Martin Caffrey, "Membrane Protein Crystallization in Lipidic Mesophases. Hosting Lipid Effects on the Crystallization and Structure of a Transmembrane Peptide," Cryst. Growth Des. 11 (4), 1182-1192 (2011). DOI: 10.1021/cg101384p

Jennifer J. Gehret, Liangcai Gu, William H. Gerwick, Peter Wipf, David H. Sherman, Janet L. Smith, "Terminal Alkene Formation by the Thioesterase of Curacin A Biosynthesis: Structure of a Decarboxylating Thioesterase," J. Biol. Chem. 286 (16), 14445-14454 (2011). DOI: 10.1074/jbc.M110.214635

Eliana Gonzales-Vigil, Christopher M. Bianchetti, George N. Phillips, Jr., Gregg A. Howe, "Adaptive evolution of threonine deaminase in plant defense against insect herbivores," Proc. Natl. Acad. Sci. USA 108 (14), 5897-5902 (2011). DOI: 10.1073/pnas.1016157108

Farisa Syeda, Rebecca L. Fagan, Matthew Wean, George V. Avvakumov, John R. Walker, Sheng Xue, Sirano Dhe-Paganon, Charles Brenner, "The Replication Focus Targeting Sequence (RFTS) Domain Is a DNA-competitive Inhibitor of Dnmt1," J. Biol. Chem. 286 (17), 15344-15351 (2011). DOI: 10.1074/jbc.M110.209882

Kayode K. Ojo, Tracy L. Arakaki, Alberto J. Napuli, Krishna K. Inampudi, Katelyn R. Keyloun, Li Zhang, Wim G.J. Hol, Christophe L.M.J. Verlind, Ethan A. Merritt, Wesley C. Van Voorhis, "Structure determination of glycogen synthase kinase-3 from Leishmania major and comparative inhibitor structure–activity relationships with Trypanosoma brucei GSK-3," Mol. Biochem. Parasit. 176 (2), 98-108 (2011). DOI: 10.1016/j.molbiopara.2010.12.009

Ruslan Sanishvili, Derek W. Yoder, Sudhir Babu Pothineni, Gerd Rosenbaum, Shenglan Xu, Stefan Vogt, Sergey Stepanov, Oleg A. Makarov, Stephen Corcoran, Richard Benn, Venugopalan Nagarajan, Janet L. Smith, Robert F. Fischetti, "Radiation damage in protein crystals is reduced with a micron-sized X-ray beam," Proc. Natl. Acad. Sci. USA 108 (15), 6127 -6132 (2011). DOI: 10.1073/pnas.1017701108

Hozefa S. Bandukwala, Yongqing Wu, Markus Feuerer, Yongheng Chen, Bianca Barboza, Srimoyee Ghosh, James C. Stroud, Christophe Benoist, Diane Mathis, Anjana Rao, Lin Chen, "Structure of a Domain-Swapped FOXP3 Dimer on DNA and Its Function in Regulatory T Cells," Immunity 34 (4), 479-491 (2011). DOI: 10.1016/j.immuni.2011.02.017

Ye Xiang, Michael G. Rossmann, "Structure of bacteriophage [phi]29 head fibers has a supercoiled triple repeating helix-turn-helix motif," Proc. Natl. Acad. Sci. USA 108 (12), 4806-4810 (2011). DOI: 10.1073/pnas.1018097108

Mauro Mileni, Joie Garfunkle, Cyrine Ezzili, Benjamin F. Cravatt, Raymond C. Stevens, Dale L. Boger, "Fluoride-Mediated Capture of a Noncovalent Bound State of a Reversible Covalent Enzyme Inhibitor: X-ray Crystallographic Analysis of an Exceptionally Potent [alpha]-Ketoheterocycle Inhibitor of Fatty Acid Amide Hydrolase," J. Am. Chem. Soc. 133 (11), 4092-4100 (2011). DOI: 10.1021/ja110877y

Aram Chang, Shanteri Singh, Craig A. Bingman, Jon S. Thorson, George N. Phillips, Jr, "Structural characterization of CalO1: a putative orsellinic acid methyltransferase in the calicheamicin-biosynthetic pathway," Acta Crystallogr. D 67 (3), 197-203 (2011). DOI: 10.1107/S090744491100360X

Vanja Avdic, Pamela Zhang, Sylvain Lanouette, Anastassia Voronova, Ilona Skerjanc, Jean-Francois Couture, "Fine-tuning the stimulation of MLL1 methyltransferase activity by a histone H3-based peptide mimetic," FASEB J. 25 (3), 960-967 (2011). DOI: 10.1096/fj.10-171959

James Wesley Fairman, Sanath Ranjan Wijerathna, Md Faiz Ahmad, Hai Xu, Ryo Nakano, Shalini Jha, Jay Prendergast, R. Martin Welin, Susanne Flodin, Annette Roos, Pär Nordlund, Zongli Li, Thomas Walz, Chris Godfrey Dealwis, "Structural basis for allosteric regulation of human ribonucleotide reductase by nucleotide-induced oligomerization," Nat. Struct. Mol. Biol. 18 (3), 316-322 (2011). DOI: 10.1038/nsmb.2007

Nicholas Noinaj, James W. Fairman, Susan K. Buchanan, "The Crystal Structure of BamB Suggests Interactions with BamA and Its Role within the BAM Complex," J. Mol. Biol. 407 (2), 248-260 (2011). DOI: 10.1016/j.jmb.2011.01.042

Shoucheng Du, Laurie Betts, Ruifeng Yang, Haibin Shi, Jason Concel, Jinwoo Ahn, Christopher Aiken, Peijun Zhang, Joanne I. Yeh, "Structure of the HIV-1 Full-Length Capsid Protein in a Conformationally Trapped Unassembled State Induced by Small-Molecule Binding," J. Mol. Biol. 406 (3), 371-386 (2011). DOI: 10.1016/j.jmb.2010.11.027

Jianyu Zhu, Andrei Korostelev, David A. Costantino, John P. Donohue, Harry F. Noller, Jeffrey S. Kieft, "Crystal structures of complexes containing domains from two viral internal ribosome entry site (IRES) RNAs bound to the 70S ribosome," Proc. Natl. Acad. Sci. USA 108 (5), 1839-1844 (2011). DOI: 10.1073/pnas.1018582108

Jens C. Krause, Damian C. Ekiert, Terrence M. Tumpey, Patricia B. Smith, Ian A. Wilson, James E. Crowe, Jr., "An Insertion Mutation That Distorts Antibody Binding Site Architecture Enhances Function of a Human Antibody," Microbiology 2 (1), e00345-1-e00345-10 (2011). DOI: 10.1128/mBio.00345-10

Jia Sun, Yuting Yang, Ke Wan, Ninghui Mao, Tai-Yuan Yu, Yi-Chien Lin, Diane C. DeZwaan, Brian C. Freeman, Jing-Jer Lin, Neal F. Lue, Ming Lei, "Structural bases of dimerization of yeast telomere protein Cdc13 and its interaction with the catalytic subunit of DNA polymerase [alpha]," Cell Res. 21, 258-274 (2011). DOI: 10.1038/cr.2010.138

Jerome Wielens, Stephen J. Headey, John J. Deadman, David I. Rhodes, Michael W. Parker, David K. Chalmers, Martin J. Scanlon, "Fragment-Based Design of Ligands Targeting a Novel Site on the Integrase Enzyme of Human Immunodeficiency Virus 1," ChemMedChem 6 (2), 258-261 (2011). DOI: 10.1002/cmdc.201000483

Dianfan Li, Jean Lee, Martin Caffrey, "Crystallizing Membrane Proteins in Lipidic Mesophases. A Host Lipid Screen," Cryst. Growth Des. 11 (2), 530-537 (2011). DOI: 10.1021/cg101378s

David Yin-wei Lin, Jianbo Diao, Daoguo Zhou, Jue Chen, "Biochemical and Structural Studies of a HECT-like Ubiquitin Ligase from Escherichia coli O157:H7," J. Biol. Chem. 286 (1), 441-449 (2011). DOI: 10.1074/jbc.M110.167643

Sudha Chakrapani, Julio F. Cordero-Morales, Vishwanath Jogini, Albert C. Pan, D. Marien Cortes, Benoît Roux, Eduardo Perozo, "On the structural basis of modal gating behavior in K[superscript +] channels," Nat. Struct. Mol. Biol. 18 (1), 67-74 (2011). DOI: 10.1038/nsmb.1968

Daniel M. Rosenbaum, Cheng Zhang, Joseph A. Lyons, Ralph Holl, David Aragao, Daniel H. Arlow, Soren G.F. Rasmussen, Hee-Jung Choi, Brian T. DeVree, Roger K. Sunahara, Pil Seok Chae, Samuel H. Gellman, Ron O. Dror, David E. Shaw, William I. Weis, Martin Caffrey, Peter Gmeiner, Brian K. Kobilka, "Structure and function of an irreversible agonist-[beta subscript 2] adrenoceptor complex," Nature 469, 236-240 (2011). DOI: 10.1038/nature09665

Soren G.F. Rasmussen, Hee-Jung Choi, Juan Jose Fung, Els Pardon, Paola Casarosa, Pil Seok Chae, Brian T. DeVree, Daniel M. Rosenbaum, Foon Sun Thian, Tong Sun Kobilka, Andreas Schnapp, Ingo Konetzki, Roger K. Sunahara, Samuel H. Gellman, Alexander Pautsch, Jan Steyaert, William I. Weis, Brian K. Kobilka, "Structure of a nanobody-stabilized active state of the [beta subscript 2] adrenoceptor," Nature 469, 175-180 (2011). DOI: 10.1038/nature09648

Petra Verdino, Deborah A. Witherden, M. Sharon Ferguson, Adam L. Corper, Andre Schiefner, Wendy L. Havran, Ian A. Wilson, "Molecular Insights into [gamma delta] T Cell Costimulation by an Anti-JAML Antibody," Structure 19 (1), 80-89 (2011). DOI: 10.1016/j.str.2010.10.007

Thomas A. Leonard, Bartosz Rozycki, Layla F. Saidi, Gerhard Hummer, James H. Hurley, "Crystal Structure and Allosteric Activation of Protein Kinase C [beta]II," Cell 144 (1), 55-66 (2011). DOI: 10.1016/j.cell.2010.12.013

Yong Tang, Marc A. Holbert, Neda Delgoshaie, Hugo Wurtele, Benoît Guillemette, Katrina Meeth, Hua Yuan, Paul Drogaris, Eun-Hye Lee, Chantal Durette, Pierre Thibault, Alain Verreault, Philip A. Cole, Ronen Marmorstein, "Structure of the Rtt109-AcCoA/Vps75 Complex and Implications for Chaperone-Mediated Histone Acetylation," Structure 19 (2), 221-231 (2011). DOI: 10.1016/j.str.2010.12.012

John B. Bruning, Ana C. Murillo, Ofelia Chacon, Raúl G. Barletta, James C. Sacchettini, "Structure of the Mycobacterium tuberculosis D-Alanine:D-Alanine Ligase, a Target of the Antituberculosis Drug D-Cycloserine," Antimicrob. Agents Ch. 55 (1), 291-301 (2011). DOI: 10.1128/AAC.00558-10

Mehabaw G. Derebe, Weizhong Zeng, Yang Li, Amer Alam, Youxing Jiang, "Structural studies of ion permeation and Ca[superscript 2+] blockage of a bacterial channel mimicking the cyclic nucleotide-gated channel pore," Proc. Natl. Acad. Sci. USA 108 (2), 592-597 (2011). DOI: 10.1073/pnas.1013643108

X. Edward Zhou, Kelly M. Suino-Powell, Yong Xu, Cee-Wah Chan, Osamu Tanabe, Schoen W. Kruse, Ross Reynolds, James Douglas Engel, H. Eric Xu, "The Orphan Nuclear Receptor TR4 Is a Vitamin A-activated Nuclear Receptor," J. Biol. Chem. 286 (4), 2877-2885 (2011). DOI: 10.1074/jbc.M110.168740

Lilia Kaustov, Hui Ouyang, Maria Amaya, Alexander Lemak, Nataliya Nady, Shili Duan, Gregory A. Wasney, Zhihong Li, Masoud Vedadi, Matthieu Schapira, Jinrong Min, Cheryl H. Arrowsmith, "Recognition and Specificity Determinants of the Human Cbx Chromodomains," J. Biol. Chem. 286 (1), 521-529 (2011). DOI: 10.1074/jbc.M110.191411

Mehabaw G. Derebe, David B. Sauer, Weizhong Zeng, Amer Alam, Ning Shi, Youxing Jiang, "Tuning the ion selectivity of tetrameric cation channels by changing the number of ion binding sites," Proc. Natl. Acad. Sci. USA 108 (2), 598-602 (2011). DOI: 10.1073/pnas.1013636108

Jennifer C. Pai, Jeffrey A. Culver, Jason E. Drury, Rakesh S. Motani, Raquel L. Lieberman, Jennifer A. Maynard, "Conversion of scFv peptide-binding specificity for crystal chaperone development," Protein Eng. Des. Sel. 24 (5), 419-428 (2011). DOI: 10.1093/protein/gzq120

Rakesh Joshi, Kwok Ki Ho, Kristen Tenney, Jui-Hui Chen, Barbara L. Golden, Frederick S. Gimble, "Evolution of I-SceI Homing Endonucleases with Increased DNA Recognition Site Specificity," J. Mol. Biol. 405 (1), 185-200 (2011). DOI: 10.1016/j.jmb.2010.10.029

Brad L. Pentelute, Kalyaneswar Mandal, Zachary P. Gates, Michael R. Sawaya, Todd O. Yeates, Stephen B.H. Kent, "Total chemical synthesis and X-ray structure of kaliotoxin by racemic protein crystallography," Chem. Commun. 46 (43), 8174-8176 (2010). DOI: 10.1039/C0CC03148H

Khawar Sohail Siddiqui, Anne Poljak, Davide De Francisci, Gea Guerriero, Oliver Pilak, Dominic Burg, Mark J. Raftery, Don M. Parkin, Jill Trewhella, Ricardo Cavicchioli, "A chemically modified [alpha]-amylase with a molten-globule state has entropically driven enhanced thermal stability," Protein Eng. Des. Sel. 23 (10), 769-780 (2010). DOI: 10.1093/protein/gzq051

Hao Chen, Chengqi Yi, Jin Zhang, Wenru Zhang, Zhiyun Ge, Cai-Guang Yang, Chuan He, "Structural insight into the oxidation-sensing mechanism of the antibiotic resistance of regulator MexR," EMBO Rep. 11 (9), 685-690 (2010). DOI: 10.1038/embor.2010.96

Can Xie, Jianghai Zhu, Xing Chen, Lizhi Mi, Noritaka Nishida, Timothy A. Springer, "Structure of an integrin with an [alpha]I domain, complement receptor type 4," EMBO J. 29, 666-679 (2010). DOI: 10.1038/emboj.2009.367

S. Agarwal, D. Hong, N.K. Desai, M. H.Sazinsky, J.M. Argüello, A.C. Rosenzweig, "Structure and interactions of the C-terminal metal binding domain of Archaeoglobus fulgidus CopA," Proteins 78 (11), 2450-2458 (2010). DOI: 10.1002/prot.22753

Lucas J. Bailey, Brian G. Fox, "Toluene 4-Monooxygenase and its Complex with Effector Protein T4moD," Encyclopedia of Inorganic Chemistry, Second Edition, R. Bruce King, eds., Wiley, 2010, online. DOI: 10.1002/9781119951438.eibc0699

Brandon Goblirsch, "Ross A. Gortner Predoctoral Fellowship," (2010).

D.W. Yoder, R. Sanishvili, S. Vogt, S. Xu, O. Makarov, R. Benn, S. Corcoran, R.F. Fischetti, "One‐Micron Beams for Macromolecular Crystallography at GM∕CA‐CAT," SRI 2009, R. Garrett, I. Gentle, K. Nugent, S. Wilkins, eds., 1234, AIP (2010), 419 - 422. DOI: 10.1063/1.3463229

Vadim Cherezov, Enrique Abola, Raymond C. Stevens, "Recent Progress in the Structure Determination of GPCRs, a Membrane Protein Family with High Potential as Pharmaceutical Targets," Membrane Protein Structure Determination , Jean-Jacques Lacapère, eds., Springer, 2010, 141 - 168. DOI: 10.1007/978-1-60761-762-4_8

Shenglan Xu, Oleg Makarov, Rich Benn, Derek W. Yoder, Sergey Stepanov, Michael Becker, Stephen Corcoran, Mark Hilgart, Venugopalan Nagarajan, Craig M. Ogata, Sudhir Pothineni, Ruslan Sanishvili, Janet L. Smith, Robert F. Fischetti, "Micro‐Crystallography Developments at GM∕CA‐CAT at the APS," SRI 2009, R. Garrett, I. Gentle, K. Nugent, S. Wilkins, eds., 1234, AIP (2010), 905 - 908. DOI: 10.1063/1.3463363

Jingwei Huang, Zan Xu, Die Wang, Craig M. Ogata, Krzysztof Palczewski, Xavier Lee, N. Martin Young, "Characterization of the secondary binding sites of Maclura pomifera agglutinin by glycan array and crystallographic analyses," Glycobiology 20 (12), 1643-1653 (2010). DOI: 10.1093/glycob/cwq118

Diwahar Narasimhan, Mark R. Nance, Daquan Gao, Mei-Chuan Ko, Joanne Macdonald, Patricia Tamburi, Dan Yoon, Donald M. Landry, James H. Woods, Chang-Guo Zhan, John J.G. Tesmer, Roger K. Sunahara, "Structural analysis of thermostabilizing mutations of cocaine esterase," Protein Eng. Des. Sel. 23 (7), 537-547 (2010). DOI: 10.1093/protein/gzq025

Andrei Korostelev, Jianyu Zhu, Haruichi Asahara, Harry F. Noller, "Recognition of the amber UAG stop codon by release factor RF1," EMBO J. 29 (15), 2577-2585 (2010). DOI: 10.1038/emboj.2010.139

Laura B. Sheard, Xu Tan, Haibin Mao, John Withers, Gili Ben-Nissan, Thomas R. Hinds, Yuichi Kobayashi, Fong-Fu Hsu, Michal Sharon, John Browse, Sheng Yang He, Josep Rizo, Gregg A. Howe, Ning Zheng, "Jasmonate perception by inositol-phosphate-potentiated COI1–JAZ co-receptor," Nature 468, 400-405 (2010). DOI: 10.1038/nature09430

Fu-Yang Lin, Chia-I Liu, Yi-Liang Liu, Yonghui Zhang, Ke Wang, Wen-Yih Jeng, Tzu-Ping Ko, Rong Cao, Andrew H.-J. Wang, Eric Oldfield, "Mechanism of action and inhibition of dehydrosqualene synthase," Proc. Natl. Acad. Sci. USA 107 (50), 21337-21342 (2010). DOI: 10.1073/pnas.1010907107

Louise Scharf, Nan-Sheng Li, Andrew J. Hawk, Diana Garzón, Tejia Zhang, Lisa M. Fox, Allison R. Kazen, Sneha Shah, Esmael J. Haddadian, Jenny E. Gumperz, Alan Saghatelian, José D. Faraldo-Gómez, Stephen C. Meredith, Joseph A. Piccirilli, Erin J. Adams, "The 2.5 Å Structure of CD1c in Complex with a Mycobacterial Lipid Reveals an Open Groove Ideally Suited for Diverse Antigen Presentation," Immunity 33 (6), 853-862 (2010). DOI: 10.1016/j.immuni.2010.11.026

Long Li, Joyce Jose, Ye Xiang, Richard J. Kuhn, Michael G. Rossmann, "Structural changes of envelope proteins during alphavirus fusion," Nature 468, 705-708 (2010). DOI: 10.1038/nature09546

Markos Koutmos, Omer Kabil, Janet L. Smith, Ruma Banerjee, "Structural basis for substrate activation and regulation by cystathionine beta-synthase (CBS) domains in cystathionine [beta]-synthase," Proc. Natl. Acad. Sci. USA 107 (49), 20958-20963 (2010). DOI: 10.1073/pnas.1011448107

Mark D. Rosen, Hariharan Venkatesan, Hillary M. Peltier, Scott D. Bembenek, Kimon C. Kanelakis, Lucy X. Zhao, Barry E. Leonard, Frances M. Hocutt, Xiaodong Wu, Heather L. Palomino, Theresa I. Brondstetter, Peter V. Haugh, Laurence Cagnon, Wen Yan, Lisa A. Liotta, Andrew Young, Tara Mirzadegan, Nigel P. Shankley, Terrance D. Barrett, Michael H. Rabinowitz, "Benzimidazole-2-pyrazole HIF Prolyl 4-Hydroxylase Inhibitors as Oral Erythropoietin Secretagogues," ACS Med. Chem. Lett. 1 (9), 526-529 (2010). DOI: 10.1021/ml100198y

Katarina Moravcevic, Jeannine M. Mendrola, Karl R. Schmitz, Yu-Hsiu Wang, David Slochower, Paul A. Janmey, Mark A. Lemmon, "Kinase Associated-1 Domains Drive MARK/PAR1 Kinases to Membrane Targets by Binding Acidic Phospholipids," Cell 143 (6), 966-977 (2010). DOI: 10.1016/j.cell.2010.11.028

Janesh Kumar, Mark L. Mayer, "Crystal Structures of the Glutamate Receptor Ion Channel GluK3 and GluK5 Amino-Terminal Domains," J. Mol. Biol. 404 (4), 680-696 (2010). DOI: 10.1016/j.jmb.2010.10.006

Jieqing Zhu, Jianghai Zhu, Ana Negri, Davide Provasi, Marta Filizola, Barry S. Coller, Timothy A. Springer, "Closed headpiece of integrin [alpah]IIb[beta]3 and its complex with an [alpha]IIb[beta]3-specific antagonist that does not induce opening," Blood 116 (23), 5050-5059 (2010). DOI: 10.1182/blood-2010-04-281154

Virginie Molle, Gulcin Gulten, Catherine Vilchèze, Romain Veyron-Churlet, Isabelle Zanella-Cléon, James C. Sacchettini, William R. Jacobs, Jr, Laurent Kremer, "Phosphorylation of InhA inhibits mycolic acid biosynthesis and growth of Mycobacterium tuberculosis," Mol. Microbiol. 78 (6), 1591-1605 (2010). DOI: 10.1111/j.1365-2958.2010.07446.x

Ye Xiang, Ulrich Baxa, Ying Zhang, Alasdair C. Steven, Gentry L. Lewis, James L. Van Etten, Michael G. Rossmann, "Crystal Structure of a Virus-Encoded Putative Glycosyltransferase," J. Virol. 84 (23), 12265-12273 (2010). DOI: 10.1128/JVI.01303-10

Bärbel Kaufmann, Valorie D. Bowman, Yi Li, Jozsef Szelei, Peter J. Waddell, Peter Tijssen, Michael G. Rossmann, "Structure of Penaeus stylirostris Densovirus, a Shrimp Pathogen," J. Virol. 84 (21), 11289-11296 (2010). DOI: 10.1128/JVI.01240-10

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Samantha J. Hyde, Brian E. Eckenroth, Brian A. Smith, William A. Eberley, Nicholas H. Heintz, Jane E. Jackman, Sylvie Doublié, "tRNA[superscript His] guanylyltransferase (THG1), a unique 3′-5′ nucleotidyl transferase, shares unexpected structural homology with canonical 5′-3′ DNA polymerases," Proc. Natl. Acad. Sci. USA 107 (47), 20305-20310 (2010). DOI: 10.1073/pnas.1010436107

Beili Wu, Ellen Y.T. Chien, Clifford D. Mol, Gustavo Fenalti, Wei Liu, Vsevolod Katritch, Ruben Abagyan, Alexei Brooun, Peter Wells, F. Christopher Bi, Damon J. Hamel, Peter Kuhn, Tracy M. Handel, Vadim Cherezov, Raymond C. Stevens, "Structures of the CXCR4 Chemokine GPCR with Small-Molecule and Cyclic Peptide Antagonists," Science 330, 1066-1071 (2010). DOI: 10.1126/science.1194396

Ellen Y.T. Chien, Wei Liu, Qiang Zhao, Vsevolod Katritch, Gye Won Han, Michael A. Hanson, Lei Shi, Amy Hauck Newman, Jonathan A. Javitch, Vadim Cherezov, Raymond C. Stevens, "Structure of the Human Dopamine D3 Receptor in Complex with a D2/D3 Selective Antagonist," Science 330, 1091-1095 (2010). DOI: 10.1126/science.1197410

Nafez Abu Tarboush, Lyndal M.R. Jensen, Manliang Feng, Hiroyasu Tachikawa, Carrie M. Wilmot, Victor L. Davidson, "Functional Importance of Tyrosine 294 and the Catalytic Selectivity for the Bis-Fe(IV) State of MauG Revealed by Replacement of This Axial Heme Ligand with Histidine," Biochemistry-US 49 (45), 9783-9791 (2010). DOI: 10.1021/bi101254p

Chengqi Yi, Guifang Jia, Guanhua Hou, Qing Dai, Wen Zhang, Guanqun Zheng, Xing Jian, Cai-Guang Yang, Qiang Cui, Chuan He, "Iron-catalysed oxidation intermediates captured in a DNA repair dioxygenase," Nature 468, 330-333 (2010). DOI: 10.1038/nature09497

Brian R. Bowman, Seongmin Lee, Shuyu Wang, Gregory L. Verdine, "Structure of Escherichia coli AlkA in Complex with Undamaged DNA," J. Biol. Chem. 285 (46), 35783-35791 (2010). DOI: 10.1074/jbc.M110.155663

Xiaoyun Su, Vinayak Agarwal, Dylan Dodd, Brian Bae, Roderick I. Mackie, Satish K. Nair, Isaac K.O. Cann, "Mutational Insights into the Roles of Amino Acid Residues in Ligand Binding for Two Closely Related Family 16 Carbohydrate Binding Modules," J. Biol. Chem. 285 (45), 34665-34676 (2010). DOI: 10.1074/jbc.M110.168302

Bärbel Kaufmann, Matthew R. Vogt, Jaap Goudsmit, Heather A. Holdaway, Anastasia A. Aksyuk, Paul R. Chipman, Richard J. Kuhn, Michael S. Diamond, Michael G. Rossmann, "Neutralization of West Nile virus by cross-linking of its surface proteins with Fab fragments of the human monoclonal antibody CR4354," Proc. Natl. Acad. Sci. USA 107 (44), 18950-18955 (2010). DOI: 10.1073/pnas.1011036107

Joanne I. Yeh, Ehmke Pohl, Daphne Truan, Wei He, George M. Sheldrick, Shoucheng Du, Catalina Achim, "The Crystal Structure of Non-Modified and Bipyridine-Modified PNA Duplexes," Chem.-Eur. J. 16 (39), 11867-11875 (2010). DOI: 10.1002/chem.201000392

Xiao He, Paul Szewczyk, Andrey Karyakin, Mariah Evin, Wen-Xu Hong, Qinghai Zhang, Geoffrey Chang, "Structure of a cation-bound multidrug and toxic compound extrusion transporter," Nature 467, 991-994 (2010). DOI: 10.1038/nature09408

Hsiu-Ju Chiu, Constantina Bakolitsa, Arne Skerra, Andrei Lomize, Dennis Carlton, Mitchell D. Miller, S. Sri Krishna, Polat Abdubek, Tamara Astakhova, Herbert L. Axelrod, Thomas Clayton, Marc C. Deller, Lian Duan, Julie Feuerhelm, Joanna C. Grant, Slawomir K. Grzechnik, Gye Won Han, Lukasz Jaroszewski, Kevin K. Jin, Heath E. Klock, Mark W. Knuth, Piotr Kozbial, Abhinav Kumar, David Marciano, Daniel McMullan, Andrew T. Morse, Edward Nigoghossian, Linda Okach, Jessica Paulsen, Ron Reyes, Christopher L. Rife, Henry van den Bedem, Dana Weekes, Qingping Xu, Keith O. Hodgson, John Wooley, Marc-Andre Elsliger, Ashley M. Deacon, Adam Godzik, Scott A. Lesley, Ian A. Wilson, "Structure of the first representative of Pfam family PF09410 (DUF2006) reveals a structural signature of the calycin superfamily that suggests a role in lipid metabolism," Acta Crystallogr. F 66 (10), 1153-1159 (2010). DOI: 10.1107/S1744309109037749

M.C. Pearce, G.A. Powers, S.C. Feil, G. Hansen, M.W. Parker, S.P. Bottomley, "Identification and Characterization of a Misfolded Monomeric Serpin Formed at Physiological Temperature," J. Mol. Biol. 403 (3), 459-467 (2010). DOI: 10.1016/j.jmb.2010.09.007

Sulochanadevi Baskaran, Peter J. Roach, Anna A. DePaoli-Roach, Thomas D. Hurley, "Structural basis for glucose-6-phosphate activation of glycogen synthase," Proc. Natl. Acad. Sci. USA 107 (41), 17563-17568 (2010). DOI: 10.1073/pnas.1006340107

Katie J. Doores, Zara Fulton, Vu Hong, Mitul K. Patel, Christopher N. Scanlan, Mark R. Wormald, M.G. Finn, Dennis R. Burton, Ian A. Wilson, Benjamin G. Davis, "A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity," Proc. Natl. Acad. Sci. USA 107 (40), 17107-17112 (2010). DOI: 10.1073/pnas.1002717107

Constantina Bakolitsa, Abhinav Kumar, Dennis Carlton, Mitchell D. Miller, S.Sri Krishna, Polat Abdubek, Tamara Astakhova, Herbert L. Axelrod, Hsiu-Ju Chiu, Thomas Clayton, Marc C. Deller, Lian Duan, Marc-André Elsliger, Julie Feuerhelm, Slawomir K. Grzechnik, Joanna C. Grant, Gye Won Han, Lukasz Jaroszewski, Kevin K. Jin, Heath E. Klock, Mark W. Knuth, Piotr Kozbial, David Marciano, Daniel McMullan, Andrew T. Morse, Edward Nigoghossian, Linda Okach, Silvya Oommachen, Jessica Paulsen, Ron Reyes, Christopher L. Rife, Henry J. Tien, Christina V. Trout, Henry van den Bedem, Dana Weekes, Qingping Xu, Keith O. Hodgson, John Wooley, Ashley M. Deacon, Adam Godzik, Scott A. Lesley, Ian A. Wilson, "Structure of LP2179, the first representative of Pfam family PF08866, suggests a new fold with a role in amino-acid metabolism," Acta Crystallogr. F 66 (10), 1205-1210 (2010). DOI: 10.1107/S1744309109023689

Paul A. Del Rizzo, Jean-François Couture, Lynnette M.A. Dirk, Bethany S. Strunk, Marijo S. Roiko, Joseph S. Brunzelle, Robert L. Houtz, Raymond C. Trievel, "SET7/9 Catalytic Mutants Reveal the Role of Active Site Water Molecules in Lysine Multiple Methylation," J. Biol. Chem. 285 (41), 31849-31858 (2010). DOI: 10.1074/jbc.M110.114587

Petra Verdino, Deborah A. Witherden, Wendy L. Havran, Ian A. Wilson, "The Molecular Interaction of CAR and JAML Recruits the Central Cell Signal Transducer PI3K," Science 329, 1210-1214 (2010). DOI: 10.1126/science.1187996

Nishant D. Shetty, Manchi C.M. Reddy, Satheesh K. Palaninathan, Joshua L. Owen, James C. Sacchettini, "Crystal structures of the apo and ATP bound Mycobacterium tuberculosis nitrogen regulatory PII protein," Protein Sci. 19 (8), 1513-1524 (2010). DOI: 10.1002/pro.430

Jingzhi Li, Wenjun Cui, Bingdong Sha, "The structural plasticity of Tom71 for mitochondrial precursor translocations," Acta Crystallogr. F 66 (9), 985-989 (2010). DOI: 10.1107/S1744309110025522

Amie K. Boal, Joseph A. Cotruvo, Jr., JoAnne Stubbe, Amy C. Rosenzweig, "Structural Basis for Activation of Class Ib Ribonucleotide Reductase," Science 329, 1526-1530 (2010). DOI: 10.1126/science.1190187

Jacqueline E. Day, Troii Hall, Lyle E. Pegg, Timothy E. Benson, Jens Hausmann, Satwik Kamtekara, "Crystallization and preliminary X-ray diffraction analysis of rat autotaxin," Acta Crystallogr. F 66 (9), 1127-1129 (2010). DOI: 10.1107/S1744309110030228

Michael G. Drage, Han-Chun Tsai, Nicole D. Pecora, Tan-Yun Cheng, Ahmad R. Arida, Supriya Shukla, Roxana E. Rojas, Chetan Seshadri, D. Branch Moody, W. Henry Boom, James C. Sacchettini, Clifford V. Harding, "Mycobacterium tuberculosis lipoprotein LprG (Rv1411c) binds triacylated glycolipid agonists of Toll-like receptor 2," Nat. Struct. Mol. Biol. 17 (9), 1088-1095 (2010). DOI: 10.1038/nsmb.1869

Nikolina Sekulic, Emily A. Bassett, Danielle J. Rogers, Ben E. Black, "The structure of (CENP-A–H4)[subscript 2] reveals physical features that mark centromeres," Nature 467, 347-351 (2010). DOI: 10.1038/nature09323

Diana Arsenieva, Jindrich Symersky, Yamin Wang, Vijayakanth Pagadala, David M. Mueller, "Crystal Structures of Mutant Forms of the Yeast F[subscript 1] ATPase Reveal Two Modes of Uncoupling," J. Biol. Chem. 285, 36561-36569 (2010). DOI: 10.1074/jbc.M110.174383

Sheng Ye, Yang Li, Youxing Jiang, "Novel insights into K[superscript +] selectivity from high-resolution structures of an open K[superscript +] channel pore," Nat. Struct. Mol. Biol. 17 (8), 1019-1023 (2010). DOI: 10.1038/nsmb.1865

Dheeraj Khare, Bo Wang, Liangcai Gu, Jamie Razelun, David H. Sherman, William H. Gerwick, Kristina Håkansson, Janet L. Smith, "Conformational switch triggered by [alpha]-ketoglutarate in a halogenase of curacin A biosynthesis," Proc. Natl. Acad. Sci. USA 107 (32), 14099-14104 (2010). DOI: 10.1073/pnas.1006738107

Brandon R. Goblirsch, Bennett R. Streit, Jennifer L. DuBois, Carrie M. Wilmot, "Structural features promoting dioxygen production by Dechloromonas aromatica chlorite dismutase," J. Biol. Inorg. Chem. 15 (6), 879-888 (2010). DOI: 10.1007/s00775-010-0651-0

Kristina Hellberg, Paul A. Grimsrud, Andrew C. Kruse, Leonard J. Banaszak, Douglas H. Ohlendorf, David A. Bernlohr, "X-ray crystallographic analysis of adipocyte fatty acid binding protein (aP2) modified with 4-hydroxy-2-nonenal," Protein Sci. 19 (8), 1480-1489 (2010). DOI: 10.1002/pro.427

Nicole Höfer, David Aragão, Martin Caffrey, "Crystallizing Transmembrane Peptides in Lipidic Mesophases," Biophys. J. 99 (3), L23-L25 (2010). DOI: 10.1016/j.bpj.2010.05.011

Vijay S. Reddy, S. Kundhavai Natchiar, Phoebe L. Stewart, Glen R. Nemerow, "Crystal Structure of Human Adenovirus at 3.5 Å Resolution," Science 329, 1071-1075 (2010). DOI: 10.1126/science.1187292

Diego Alvarado, Daryl E. Klein, Mark A. Lemmon, "Structural Basis for Negative Cooperativity in Growth Factor Binding to an EGF Receptor," Cell 142 (4), 568-579 (2010). DOI: 10.1016/j.cell.2010.07.015

Dong Yang, James H. Hurley, "Structural Role of the Vps4-Vta1 Interface in ESCRT-III Recycling," Structure 18 (8), 976-984 (2010). DOI: 10.1016/j.str.2010.04.014

Lawrence K. Lee, Michael A. Ginsburg, Claudia Crovace, Mhairi Donohoe, Daniela Stock, "Structure of the torque ring of the flagellar motor and the molecular basis for rotational switching," Nature 466, 996-1000 (2010). DOI: 10.1038/nature09300

Jui-Hui Chen, Rieko Yajima, Durga M. Chadalavada, Elaine Chase, Philip C. Bevilacqua, Barbara L. Golden, "A 1.9 Å Crystal Structure of the HDV Ribozyme Precleavage Suggests both Lewis Acid and General Acid Mechanisms Contribute to Phosphodiester Cleavage," Biochemistry-US 49 (31), 6508-6518 (2010). DOI: 10.1021/bi100670p

Jamie B. Scaglione, David L. Akey, Rachel Sullivan, Jeffrey D. Kittendorf, Christopher M. Rath, Eung-Soo Kim, Janet L. Smith, David H. Sherman, "Biochemical and Structural Characterization of the Tautomycetin Thioesterase: Analysis of a Stereoselective Polyketide Hydrolase," Angew. Chem. Int. Ed. 49 (33), 5726-5730 (2010). DOI: 10.1002/anie.201000032

Daniel Wacker, Gustavo Fenalti, Monica A. Brown, Vsevolod Katritch, Ruben Abagyan, Vadim Cherezov, Raymond C. Stevens, "Conserved Binding Mode of Human [beta subscript 2] Adrenergic Receptor Inverse Agonists and Antagonist Revealed by X-ray Crystallography," J. Am. Chem. Soc. 132 (33), 11443-11445 (2010). DOI: 10.1021/ja105108q

Luis G. Cuello, Vishwanath Jogini, D. Marien Cortes, Albert C. Pan, Dominique G. Gagnon, Olivier Dalmas, Julio F. Cordero-Morales, Sudha Chakrapani, Benoît Roux, Eduardo Perozo, "Structural basis for the coupling between activation and inactivation gates in K[superscript +] channels," Nature 466, 272-275 (2010). DOI: 10.1038/nature09136

Yunkun Wu, Yi Yang, Sheng Ye, Youxing Jiang, "Structure of the gating ring from the human large-conductance Ca[superscript 2+]-gated K[superscript +] channel," Nature 466, 393-397 (2010). DOI: 10.1038/nature09252

Luis G. Cuello, Vishwanath Jogini, D. Marien Cortes, Eduardo Perozo, "Structural mechanism of C-type inactivation in K[superscript +] channels," Nature 466, 203-208 (2010). DOI: 10.1038/nature09153

Lianghua Lu, Chengqi Yi, Xing Jian, Guanqun Zheng, Chuan He, "Structure determination of DNA methylation lesions N[superscript 1]-meA and N[superscript 3]-meC in duplex DNA using a cross-linked protein–DNA system," Nucleic Acids Res. 38 (13), 4415-4425 (2010). DOI: 10.1093/nar/gkq129

Mauro Mileni, Satwik Kamtekar, David C. Wood, Timothy E. Benson, Benjamin F. Cravatt, Raymond C. Stevens, "Crystal Structure of Fatty Acid Amide Hydrolase Bound to the Carbamate Inhibitor URB597: Discovery of a Deacylating Water Molecule and Insight into Enzyme Inactivation," J. Mol. Biol. 400 (4), 743-754 (2010). DOI: 10.1016/j.jmb.2010.05.034

Kristie D. Goodwin, Hongzhen He, Tsuyoshi Imasaki, Suk-Hee Lee, Millie M. Georgiadis, "Crystal Structure of the Human Hsmar1-Derived Transposase Domain in the DNA Repair Enzyme Metnase," Biochemistry-US 49 (27), 5705-5713 (2010). DOI: 10.1021/bi100171x

Elif Eren, Megan Murphy, Jon Goguen, Bert van den Berg, "An Active Site Water Network in the Plasminogen Activator Pla from Yersinia pestis," Structure 18 (7), 809-818 (2010). DOI: 10.1016/j.str.2010.03.013

Juha P. Himanen, Laila Yermekbayeva, Peter W. Janes, John R. Walker, Kai Xu, Lakmali Atapattu, Kanagalaghatta R. Rajashankar, Anneloes Mensinga, Martin Lackmann, Dimitar B. Nikolov, Sirano Dhe-Paganon, "Architecture of Eph receptor clusters," Proc. Natl. Acad. Sci. USA 107 (24), 10860-10865 (2010). DOI: 10.1073/pnas.1004148107

Kuo-Chiang Hsia, André Hoelz, "Crystal structure of [alpha]-COP in complex with [epsilon]-COP provides insight into the architecture of the COPI vesicular coat," Proc. Natl. Acad. Sci. USA 107 (25), 11271-11276 (2010). DOI: 10.1073/pnas.1006297107

Emily Lorenzini, Alexander Singer, Bhag Singh, Robert Lam, Tatiana Skarina, Nickolay Y. Chirgadze, Alexei Savchenko, Radhey S. Gupta, "Structure and Protein-Protein Interaction Studies on Chlamydia trachomatis Protein CT670 (YscO Homolog)," J. Bacteriol. 192 (11), 2746-2756 (2010). DOI: 10.1128/JB.01479-09

Yi Ren, Hyuk-Soo Seo, Günter Blobel, André Hoelz, "Structural and functional analysis of the interaction between the nucleoporin Nup98 and the mRNA export factor Rae1," Proc. Natl. Acad. Sci. USA 107 (23), 10406-10411 (2010). DOI: 10.1073/pnas.1005389107

Donald D. Raymond, Mary E. Piper, Sonja R. Gerrard, Janet L. Smith, "Structure of the Rift Valley fever virus nucleocapsid protein reveals another architecture for RNA encapsidation," Proc. Natl. Acad. Sci. USA 107 (26), 11769-11774 (2010). DOI: 10.1073/pnas.1001760107

Robert Pejchal, Laura M. Walker, Robyn L. Stanfield, Sanjay K. Phogat, Wayne C. Koff, Pascal Poignard, Dennis R. Burton, Ian A. Wilson, "Structure and function of broadly reactive antibody PG16 reveal an H3 subdomain that mediates potent neutralization of HIV-1," Proc. Natl. Acad. Sci. USA 107 (25), 11483-11488 (2010). DOI: 10.1073/pnas.1004600107

Sung-il Yoon, Minsun Hong, Gye Won Han, Ian A. Wilson, "Crystal structure of soluble MD-1 and its interaction with lipid IVa," Proc. Natl. Acad. Sci. USA 107 (24), 10990-10995 (2010). DOI: 10.1073/pnas.1004153107

Liang Li, Qiang Fu, Christopher A. Kors, Lance Stewart, Peter Nollert, Philip D. Laible, Rustem F. Ismagilov, "A plug-based microfluidic system for dispensing lipidic cubic phase (LCP) material validated by crystallizing membrane proteins in lipidic mesophases," Microfluid. Nanofluid. 8 (6), 789-798 (2010). DOI: 10.1007/s10404-009-0512-8

V.S. Reddy, S.K. Natchiar, L. Gritton, T.-M. Mullen, P.L. Stewart, G.R. Nemerow, "Crystallization and preliminary X-ray diffraction analysis of human adenovirus," Virology 402 (1), 209-214 (2010). DOI: 10.1016/j.virol.2010.03.028

Istvan Botos, Nadim Majdalani, Stephen J. Mayclin, Jennifer Gehret McCarthy, Karl Lundquist, Damian Wojtowicz, Travis J. Barnard, James C. Gumbart, Susan K. Buchanan, "Structural and Functional Characterization of the LPS Transporter LptDE from Gram-Negative Pathogens," Structure 24 (6), 965-976 (2010). DOI: 10.1016/j.str.2016.03.026

Radhika Malik, Ronald E. Viola, "Structural characterization of tartrate dehydrogenase: a versatile enzyme catalyzing multiple reactions," Acta Crystallogr. D 66 (6), 673-684 (2010). DOI: 10.1107/S0907444910008851

Christian Biertümpfel, Ye Zhao, Yuji Kondo, Santiago Ramón-Maiques, Mark Gregory, Jae Young Lee, Chikahide Masutani, Alan R. Lehmann, Fumio Hanaoka, Wei Yang, "Structure and mechanism of human DNA polymerase [eta]," Nature 465, 1044-1048 (2010). DOI: 10.1038/nature09196

David A. Boudreaux, Tushar K. Maiti, Christopher W. Davies, Chittaranjan Das, "Ubiquitin vinyl methyl ester binding orients the misaligned active site of the ubiquitin hydrolase UCHL1 into productive conformation," Proc. Natl. Acad. Sci. USA 107 (20), 9117-9122 (2010). DOI: 10.1073/pnas.0910870107

Bum Soo Hong, Abdellah Allali-Hassani, Wolfram Tempel, Patrick J. Finerty, Jr., Farrell MacKenzie, Svetoslav Dimov, Masoud Vedadi, Hee-Won Park, "Crystal Structures of Human Choline Kinase Isoforms in Complex with Hemicholinium-3 Single Amino Acid near the Active Site Influences Inhibitor Sensitivity," J. Biol. Chem. 285 (21), 16330-16340 (2010). DOI: 10.1074/jbc.M109.039024

N. Li, P. Yun, M.A. Nadkarni, N.B. Ghadikolaee, K.A. Nguyen, M. Lee, N. Hunter, C.A. Collyer, "Structure determination and analysis of a haemolytic gingipain adhesin domain from Porphyromonas gingivalis," Mol. Microbiol. 76 (4), 861-873 (2010). DOI: 10.1111/j.1365-2958.2010.07123.x

Kenji Yoshida, Adam L. Corper, Rana Herro, Bana Jabri, Ian A. Wilson, Luc Teyton, "The diabetogenic mouse MHC class II molecule I-A[superscript g7] is endowed with a switch that modulates TCR affinity," J. Clin. Invest. 120 (5), 1578-1590 (2010). DOI: 10.1172/JCI41502

Tyson R. Shepherd, Suzi M. Klaus, Xu Liu, S. Ramaswamy, Kris A. DeMali, Ernesto J. Fuentes, "The Tiam1 PDZ Domain Couples to Syndecan1 and Promotes Cell–Matrix Adhesion," J. Mol. Biol. 398 (5), 730-746 (2010). DOI: 10.1016/j.jmb.2010.03.047

Nadine L. Samara, Ajit B. Datta, Christopher E. Berndsen, Xiangbin Zhang, Tingting Yao, Robert E. Cohen, Cynthia Wolberger, "Structural Insights into the Assembly and Function of the SAGA Deubiquitinating Module," Science 328, 1025-1029 (2010). DOI: 10.1126/science.1190049

William J. Zuercher, Richard G. Buckholz†, Nino Campobasso, Jon L. Collins, Cristin M. Galardi, Robert T. Gampe, Stephen M. Hyatt, Susan L. Merrihew, John T. Moore, Jeffrey A. Oplinger, Paul R. Reid, Paul K. Spearing, Thomas B. Stanley, Eugene L. Stewart, Timothy M. Willson, "Discovery of Tertiary Sulfonamides as Potent Liver X Receptor Antagonists," J. Med. Chem. 53 (8), 3412-3416 (2010). DOI: 10.1021/jm901797p

Jerome Wielens, Stephen J. Headey, Dharshini Jeevarajah, David I. Rhodes, John Deadman, David K. Chalmers, Martin J. Scanlon, Michael W. Parker, "Crystal structure of the HIV-1 integrase core domain in complex with sucrose reveals details of an allosteric inhibitory binding site," FEBS Lett. 584 (8), 1455-1462 (2010). DOI: 10.1016/j.febslet.2010.03.016

Rui Xu, Damian C. Ekiert, Jens C. Krause, Rong Hai, James E. Crowe, Jr., Ian A. Wilson, "Structural Basis of Preexisting Immunity to the 2009 H1N1 Pandemic Influenza Virus," Science 328, 357-360 (2010). DOI: 10.1126/science.1186430

Stacie L. Bulfer, Erin M. Scott, Lorraine Pillus, Raymond C. Trievel, "Structural Basis for l-Lysine Feedback Inhibition of Homocitrate Synthase," J. Biol. Chem. 285 (14), 10446-10453 (2010). DOI: 10.1074/jbc.M109.094383

Nardy Lampl, Ofra Budai-Hadrian, Olga Davydov, Tom V. Joss, Stephen J. Harrop, Paul M.G. Curmi, Thomas H. Roberts, Robert Fluhr, "Arabidopsis AtSerpin1, Crystal Structure and in Vivo Interaction with Its Target Protease RESPONSIVE TO DESICCATION-21 (RD21)," J. Biol. Chem. 285 (18), 13550-13560 (2010). DOI: 10.1074/jbc.M109.095075

Jianbo Dong, Aaron A. Thompson, Yongfeng Fan, Jianlong Lou, Fraser Conrad, Mengfei Ho, Melissa Pires-Alves, Brenda A. Wilson, Raymond C. Stevens, James D. Marks, "A Single-Domain Llama Antibody Potently Inhibits the Enzymatic Activity of Botulinum Neurotoxin by Binding to the Non-Catalytic [alpha]-Exosite Binding Region," J. Mol. Biol. 397 (4), 1106-1118 (2010). DOI: 10.1016/j.jmb.2010.01.070

Pål Stenmark, Min Dong, Jérôme Dupuy, Edwin R. Chapman, Raymond C. Stevens, "Crystal Structure of the Botulinum Neurotoxin Type G Binding Domain: Insight into Cell Surface Binding," J. Mol. Biol. 397 (5), 1287-1297 (2010). DOI: 10.1016/j.jmb.2010.02.041

Fumin Shi, Shannon E. Telesco, Yingting Liu, Ravi Radhakrishnan, Mark A. Lemmon, "ErbB3/HER3 intracellular domain is competent to bind ATP and catalyze autophosphorylation," Proc. Natl. Acad. Sci. USA 107 (17), 7692-7697 (2010). DOI: 10.1073/pnas.1002753107

Sumana Chandramouli, Jeremiah S. Joseph, Sophie Daudenarde, Jovylyn Gatchalian, Cromwell Cornillez-Ty, Peter Kuhn, "Serotype-Specific Structural Differences in the Protease-Cofactor Complexes of the Dengue Virus Family," J. Virol. 84 (6), 3059-3067 (2010). DOI: 10.1128/JVI.02044-09

Jianhong Chen, Nicolas Villanueva, Mark A. Rould, Scott W. Morrical, "Insights into the mechanism of Rad51 recombinase from the structure and properties of a filament interface mutant," Nucleic Acids Res. 38 (14), 4889-4906 (2010). DOI: 10.1093/nar/gkq209

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Lyndal M.R. Jensen, Ruslan Sanishvili, Victor L. Davidson, Carrie M. Wilmot, "In Crystallo Posttranslational Modification Within a MauG/Pre–Methylamine Dehydrogenase Complex," Science 327, 1392-1394 (2010). DOI: 10.1126/science.1182492

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Marcin Golczak, Philip D. Kiser, David T. Lodowski, Akiko Maeda, Krzysztof Palczewski, "Importance of Membrane Structural Integrity for RPE65 Retinoid Isomerization Activity," J. Biol. Chem. 285 (13), 9667-9682 (2010). DOI: 10.1074/jbc.M109.063941

Matthew Hogg, Jean Rudnicki, John Midkiff, Linda Reha-Krantz, Sylvie Doubli, Susan S. Wallace, "Kinetics of Mismatch Formation opposite Lesions by the Replicative DNA Polymerase from Bacteriophage RB69," Biochemistry-US 49 (11), 2317-2325 (2010). DOI: 10.1021/bi901488d

Pierre Aller, Yu Ye, Susan S. Wallace, Cynthia J. Burrows, Sylvie Doubli, "Crystal Structure of a Replicative DNA Polymerase Bound to the Oxidized Guanine Lesion Guanidinohydantoin," Biochemistry-US 49 (11), 2502-2509 (2010). DOI: 10.1021/bi902195p

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Patricia V. Burgos, Gonzalo A. Mardones, Adriana L. Rojas, Luis L.P. daSilva, Yogikala Prabhu, James H. Hurley, Juan S. Bonifacino, "Sorting of the Alzheimer's Disease Amyloid Precursor Protein Mediated by the AP-4 Complex," Dev. Cell 18 (3), 425-436 (2010). DOI: 10.1016/j.devcel.2010.01.015

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Yan-Feng Zhou, Timothy A. Springer, "Highly reinforced structure of a C-terminal dimerization domain in von Willebrand factor," Blood 123 (12), 1785-1793 (2010). DOI: 10.1182/blood-2013-11-523639

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Michael J. Lowden, Karen Skorupski, Maria Pellegrini, Michael G. Chiorazzo, Ronald K. Taylor, F. Jon Kull, "Structure of Vibrio cholerae ToxT reveals a mechanism for fatty acid regulation of virulence genes," Proc. Natl. Acad. Sci. USA 107 (7), 2860-2865 (2010). DOI: 10.1073/pnas.0915021107

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K. Reed Clark, Scott T.R. Walsh, "Crystal structure of a 3B3 variant - A broadly neutralizing HIV-1 scFv antibody," Protein Sci. 18 (12), 2429-2441 (2009). DOI: 10.1002/pro.255

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Manchi C.M. Reddy, Satheesh K. Palaninathan, John B. Bruning, Cory Thurman, Danielle Smith, James C. Sacchettini, "Structural Insights into the Mechanism of the Allosteric Transitions of Mycobacterium tuberculosis cAMP Receptor Protein," J. Biol. Chem. 284 (52), 36581-36591 (2009). DOI: 10.1074/jbc.M109.041343

Deyu Zhu, Craig R. Stumpf, Joseph M. Krahn, Marvin Wickens, Traci M. Tanaka Hall, "A 5′ cytosine binding pocket in Puf3p specifies regulation of mitochondrial mRNAs," Proc. Natl. Acad. Sci. USA 106 (48), 20192-20197 (2009). DOI: 10.1073/pnas.0812079106

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Hee-Jung Choi, Julia C. Gross, Sabine Pokutta, William I. Weis, "Interactions of Plakoglobin and [beta]-Catenin with Desmosomal Cadherins BASIS OF SELECTIVE EXCLUSION OF [alpha]- AND [beta]-CATENIN FROM DESMOSOMES," J. Biol. Chem. 284, 31776-31788 (2009). DOI: 10.1074/jbc.M109.047928

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Junbin Hu, Jingzhi Li, Xinguo Qian, Vlad Denic, Bingdong Sha, "The Crystal Structures of Yeast Get3 Suggest a Mechanism for Tail-Anchored Protein Membrane Insertion," PLoS One 4 (11), e8061-1-e8061-7 (2009). DOI: 10.1371/journal.pone.0008061

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Yufeng Tong, Wolfram Tempel, Lyudmila Nedyalkova, Farrell MacKenzie, Hee-Won Park, "Crystal Structure of the N-Acetylmannosamine Kinase Domain of GNE," PLoS One 4 (10), e7165-1-e7165-9 (2009). DOI: 10.1371/journal.pone.0007165

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Martin Laurberg, Haruichi Asahara, Andrei Korostelev, Jianyu Zhu, Sergei Trakhanov, Harry F. Noller, "Structural basis for translation termination on the 70S ribosome," Nature 454, 852-857 (2008). DOI: 10.1038/nature07115

Jill E. Chrencik, Alexei Brooun, Hui Zhang, Irimpan I. Mathews, Greg L. Hura, Scott A. Foster, J. Jefferson P. Perry, Markus Streiff, Paul Ramage, Hans Widmer, Gary M. Bokoch, John A. Tainer, Gisbert Weckbecker, Peter Kuhn, "Structural Basis of Guanine Nucleotide Exchange Mediated by the T-Cell Essential Vav1," J. Mol. Biol. 380 (5), 828-843 (2008). DOI: 10.1016/j.jmb.2008.05.024

Jessica Momb, Canhui Wang, Dali Liu, Pei W. Thomas, Gregory A. Petsko, Hua Guo, Dagmar Ringe, Walter Fast, "Mechanism of the Quorum-Quenching Lactonase (AiiA) from Bacillus thuringiensis. 2. Substrate Modeling and Active Site Mutations," Biochemistry-US 47 (29), 7715-7725 (2008). DOI: 10.1021/bi8003704

Elizabeth A. Feeser, Cynthia Wolberger, "Structural and Functional Studies of the Rap1 C-Terminus Reveal Novel Separation-of-Function Mutants," J. Mol. Biol. 380 (3), 520-531 (2008). DOI: 10.1016/j.jmb.2008.04.078

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Daryl E. Klein, Steven E. Stayrook, Fumin Shi, Kartik Narayan, Mark A. Lemmon, "Structural basis for EGFR ligand sequestration by Argos," Nature 453, 1271-1275 (2008). DOI: 10.1038/nature06978

Michael A. Hanson, Vadim Cherezov, Mark T. Griffith, Christopher B. Roth, Veli-Pekka Jaakola, Ellen Y.T. Chien, Jeffrey Velasquez, Peter Kuhn, Raymond C. Stevens, "A Specific Cholesterol Binding Site Is Established by the 2.8 Å Structure of the Human [beta][subscript 2]-Adrenergic Receptor," Structure 16 (6), 897-905 (2008). DOI: 10.1016/j.str.2008.05.001

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Piotr Kozbial, Qingping Xu, Hsiu-Ju Chiu, Daniel McMullan, S. Sri Krishna, Mitchell D. Miller, Polat Abdubek, Claire Acosta, Tamara Astakhova, Herbert L. Axelrod, Dennis Carlton, Thomas Clayton, Marc Deller, Lian Duan, Ylva Elias, Marc-André Elsliger, Julie Feuerhelm, Slawomir K. Grzechnik, Joanna Hale, Gye Won Han, Lukasz Jaroszewski, Kevin K. Jin, Heath E. Klock, Mark W. Knuth, Eric Koesema, Abhinav Kumar, David Marciano, Andrew T. Morse, Kevin D. Murphy, Edward Nigoghossian, Linda Okach, Silvya Oommachen, Ron Reyes, Christopher L. Rife, Glen Spraggon, Christina V. Trout, Henry ban den Bedem, Dana Weekes, Aprilfawn White, Guenter Wolf, Chloe Zubieta, Keith O. Hodgson, John Wooley, Ashley M. Deacon, Adam Godzik, Scott A. Lesley, Ian A. Wilson, "Crystal structures of MW1337R and lin2004: Representatives of a novel protein family that adopt a four-helical bundle fold," Proteins 71 (3), 1589-1596 (2008). DOI: 10.1002/prot.22020

Puja Singh, Benlian Wang, Tadao Maeda, Krzysztof Palczewski, John J.G. Tesmer, "Structures of Rhodopsin Kinase in Different Ligand States Reveal Key Elements Involved in G Protein-coupled Receptor Kinase Activation," J. Biol. Chem. 283 (20), 14053-14062 (2008). DOI: 10.1074/jbc.M708974200

Jin Huang, Akiko Koide, Koki Makabe, Shohei Koide, "Design of protein function leaps by directed domain interface evolution," Proc. Natl. Acad. Sci. USA 105 (18), 6578-6583 (2008). DOI: 10.1073/pnas.0801097105

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L. Gan, J.E. Johnson, "An optimal exposure strategy for cryoprotected virus crystals with lattice constants greater than 1000 Å," J. Synchrotron Rad. 15 (3), 223-226 (2008). DOI: 10.1107/S0909049507064813

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Longsheng Lai, Zhaohui Xu, Jiahai Zhou, Kyung-Dall Lee, Gordon L. Amidon, "Molecular Basis of Prodrug Activation by Human Valacyclovirase, an [alpha]-Amino Acid Ester Hydrolase," J. Biol. Chem. 283 (14), 9318-9327 (2008). DOI: 10.1074/jbc.M709530200

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David B. Langley, Derek W.S. Harty, Nicholas A. Jacques, Neil Hunter, J. Mitchell Guss, Charles A. Collyer, "Structure of N-acetyl-[beta]-D-glucosaminidase (GcnA) from the Endocarditis Pathogen Streptococcus gordonii and its Complex with the Mechanism-based Inhibitor NAG-thiazoline," J. Mol. Biol. 377 (1), 104-116 (2008). DOI: 10.1016/j.jmb.2007.09.028

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Supratim Datta, Markos Koutmos, Katherine A. Pattridge, Martha L. Ludwig, Rowena G. Matthews, "A disulfide-stabilized conformer of methionine synthase reveals an unexpected role for the histidine ligand of the cobalamin cofactor," Proc. Natl. Acad. Sci. USA 105 (11), 4115-4120 (2008). DOI: 10.1073/pnas.0800329105

I-Mei Yu, Wei Zhang, Heather A. Holdaway, Long Li, Victor A. Kostyuchenko, Paul R. Chipman, Richard J. Kuhn, Michael G. Rossmann, Jue Chen, "Structure of the Immature Dengue Virus at Low pH Primes Proteolytic Maturation," Science 319 (5871), 1834-1837 (2008). DOI: 10.1126/science.1153264

Johanne Le Coq, Alexander Pavlovsky, Radhika Malik, Ruslan Sanishvili, Chengfu Xu, Ronald E. Viola, "Examination of the Mechanism of Human Brain Aspartoacylase through the Binding of an Intermediate Analogue," Biochemistry-US 47 (11), 3484-3492 (2008). DOI: 10.1021/bi702400x

Kaiser C. Shen, Dorota A. Kuczynska, Irene J. Wu, Beverly H. Murray, Lauren R. Sheckler, Gabby Rudenko, "Regulation of Neurexin 1[beta] Tertiary Structure and Ligand Binding through Alternative Splicing," Structure 16, 422-431 (2008). DOI: 10.1016/j.str.2008.01.005

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Andrei Fokine, Konstantin A. Miroshnikov, Mikhail M. Shneider, Vadim V. Mesyanzhinov, Michael G. Rossmann, "Structure of the Bacteriophage [phi]KZ Lytic Transglycosylase gp144," J. Biol. Chem. 283 (11), 7242-7250 (2008). DOI: 10.1074/jbc.M709398200

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Ralf Jauch, Calista Keow Leng Ng, Kumar Singh Saikatendu, Raymond C. Stevens, Prasanna R. Kolatkar, "Crystal Structure and DNA Binding of the Homeodomain of the Stem Cell Transcription Factor Nanog," J. Mol. Biol. 376 (3), 758-770 (2008). DOI: 10.1016/j.jmb.2007.11.091

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Min Guo, Michael Ignatov, Karin Musier-Forsyth, Paul Schimmel, Xiang-Lei Yang, "Crystal structure of tetrameric form of human lysyl-tRNA synthetase: Implications for multisynthetase complex formation," Proc. Natl. Acad. Sci. USA 105 (7), 2331-2336 (2008). DOI: 10.1073/pnas.0712072105

Jason W. Johnston, Nathan P. Coussens, Simon Allen, Jon C.D. Houtman, Keith H. Turner, Anthony Zaleski, S. Ramaswamy, Bradford W. Gibson, Michael A. Apicella, "Characterization of the N-Acetyl-5-neuraminic Acid-binding Site of the Extracytoplasmic Solute Receptor (SiaP) of Nontypeable Haemophilus influenzae Strain 2019," J. Biol. Chem. 283 (2), 855-865 (2008). DOI: 10.1074/jbc.M706603200

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Jianbo Diao, Ying Zhang, Jon M. Huibregtse, Daoguo Zhou, Jue Chen, "Crystal structure of SopA, a Salmonella effector protein mimicking a eukaryotic ubiquitin ligase," Nat. Struct. Mol. Biol. 15 (1), 65-70 (2008). DOI: 10.1038/nsmb1346

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Jing-Dong Ye, Valentina Tereshko, John K. Frederiksen, Akiko Koide, Frederic A. Fellouse, Sachdev S. Sidhu, Shohei Koide, Anthony A. Kossiakoff, Joseph A. Piccirilli, "Synthetic antibodies for specific recognition and crystallization of structured RNA," Proc. Natl. Acad. Sci. USA 105 (1), 82-87 (2008). DOI: 10.1073/pnas.0709082105

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Stephen C. Graham, J. Mitchell Guss, "Complexes of mutants of Escherichia coli aminopeptidase P and the tripeptide substrate ValProLeu," Arch. Biochem. Biophys. 469 (2), 200-208 (2008). DOI: 10.1016/j.abb.2007.10.009

Junyu Xiao, Hengchuan Xia, Jiahai Zhou, Ishara F. Azmi, Brian A. Davies, David J. Katzmann, Zhaohui Xu, "Structural Basis of Vta1 Function in the Multivesicular Body Sorting Pathway," Dev. Cell 14 (1), 37-49 (2008). DOI: 10.1016/j.devcel.2007.10.013

Christopher D. Fleming, Carol C. Edwards, Stephen D. Kirby, Donald M. Maxwell, Philip M. Potter, Douglas M. Cerasoli, Matthew R. Redinbo, "Crystal Structures of Human Carboxylesterase 1 in Covalent Complexes with the Chemical Warfare Agents Soman and Tabun," Biochemistry-US 46 (17), 5063-5071 (2007). DOI: 10.1021/bi700246n

J. Alejandro D'Aquino, Judith R. Lattimer, Andrew Denninger, Katharine E. D'Aquino, Dagmar Ringe, "Role of the N-Terminal Helix in the Metal Ion-Induced Activation of the Diphtheria Toxin Repressor DtxR," Biochemistry-US 46 (42), 11761-11770 (2007). DOI: 10.1021/bi7007883

Siyang Sun, Kiran Kondabagil, Petra M. Gentz, Michael G. Rossmann, Venigalla B. Rao, "The Structure of the ATPase that Powers DNA Packaging into Bacteriophage T4 Procapsids," Mol. Cell 25 (6), 943-949 (2007). DOI: 10.1016/j.molcel.2007.02.013

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Alexei Savchenko, Michael Proudfoot, Tatiana Skarina, Alexander Singer, Olga Litvinova, Ruslan Sanishvili, Greg Brown, Nickolay Chirgadze, Alexander F. Yakunin, "Molecular Basis of the Antimutagenic Activity of the House-Cleaning Inosine Triphosphate Pyrophosphatase RdgB from Escherichia coli," J. Mol. Biol. 374 (4), 1091-1103 (2007). DOI: 10.1016/j.jmb.2007.10.012

Jill E. Chrencik, Alexei Brooun, Michael I. Recht, George Nicola, Leila K. Davis, Ruben Abagyan, Hans Widmer, Elena B. Pasquale, Peter Kuhn, "Three-dimensional Structure of the EphB2 Receptor in Complex with an Antagonistic Peptide Reveals a Novel Mode of Inhibition," J. Biol. Chem. 282 (50), 36505-36513 (2007). DOI: 10.1074/jbc.M706340200

Christopher M. Bianchetti, Li Yi, Stephen W. Ragsdale, George N. Phillips, Jr., "Comparison of Apo- and Heme-bound Crystal Structures of a Truncated Human Heme Oxygenase-2," J. Biol. Chem. 282 (52), 37624-37631 (2007). DOI: 10.1074/jbc.M707396200

Yufeng Tong, Preeti Chugha, Prasanta K. Hota, Rebecca S. Alviani, Mei Li, Wolfram Tempel, Limin Shen, Hee-Won Park, Matthias Buck, "Binding of Rac1, Rnd1, and RhoD to a Novel Rho GTPase Interaction Motif Destabilizes Dimerization of the Plexin-B1 Effector Domain," J. Biol. Chem. 282 (51), 37215-37224 (2007). DOI: 10.1074/jbc.M703800200

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Liangcai Gu, Todd W. Geders, Bo Wang, William H. Gerwick, Kristina Hakansson, Janet L. Smith, David H. Sherman, "GNAT-Like Strategy for Polyketide Chain Initiation," Science 318, 970-974 (2007). DOI: 10.1126/science.1148790

Andrew Robinson, Amy P. Guilfoyle, Stephen J. Harrop, Yan Boucher, H.W. Stokes, Paul M.G. Curmi, Bridget C. Mabbutt, "A putative house-cleaning enzyme encoded within an integron array: 1.8 Å crystal structure defines a new MazG subtype," Mol. Microbiol. 66 (3), 610-621 (2007). DOI: 10.1111/j.1365-2958.2007.05932.x

Junyu Xiao, Hengchuan Xia, Kae Yoshino-Koh, Jiahai Zhou, Zhaohui Xu, "Structural Characterization of the ATPase Reaction Cycle of Endosomal AAA Protein Vps4," J. Mol. Biol. 374 (3), 655-670 (2007). DOI: 10.1016/j.jmb.2007.09.067

Akiko Koide, Valentina Tereshko, Serdar Uysal, Katrina Margalef, Anthony A. Kossiakoff, Shohei Koide, "Exploring the Capacity of Minimalist Protein Interfaces: Interface Energetics and Affinity Maturation to Picomolar K[subscript D] of a Single-domain Antibody with a Flat Paratope," J. Mol. Biol. 373 (4), 941-953 (2007). DOI: 10.1016/j.jmb.2007.08.027

Michael L. Oldham, Dheeraj Khare, Florante A. Quiocho, Amy L. Davidson, Jue Chen, "Crystal structure of a catalytic intermediate of the maltose transporter," Nature 450, 515-521 (2007). DOI: 10.1038/nature06264

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Xin Liu, Ronen Marmorstein, "Structure of the retinoblastoma protein bound to adenovirus E1A reveals the molecular basis for viral oncoprotein inactivation of a tumor suppressor," Gene Dev. 21 (21), 2711-2716 (2007). DOI: 10.1101/gad.1590607

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Koki Makabe, Shude Yan, Valentina Tereshko, Grzegorz Gawlak, Shohei Koide, "[Beta]-strand Flipping and Slipping Triggered by Turn Replacement Reveal the Opportunistic Nature of [Beta]-strand Pairing," J. Am. Chem. Soc. 129 (47), 14661-14669 (2007). DOI: 10.1021/ja074252c

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Roman Aranda IV, Chad E. Worley, Mengyao Liu, Eduard Bitto, M. Susan Cates, John S. Olson, Benfang Lei, George N. Phillips, Jr., "Bis-methionyl Coordination in the Crystal Structure of the Heme-binding Domain of the Streptococcal Cell Surface Protein Shp," J. Mol. Biol. 374 (2), 374-383 (2007). DOI: 10.1016/j.jmb.2007.08.058

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Manchi C.M. Reddy, Satheesh K. Palaninathan, Nishant D. Shetty, Joshua L. Owen, Misty D. Watson, James C. Sacchettini, "High Resolution Crystal Structures of Mycobacterium tuberculosis Adenosine Kinase: Insights into the Mechanism and Specificity of this Novel Prokaryotic Enzyme," J. Biol. Chem. 282 (37), 27334-27342 (2007). DOI: 10.1074/jbc.M703290200

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Jean-Francois Couture, Evys Collazo, Patricia A. Ortiz-Tello, Joseph S. Brunzelle, Raymond C. Trievel, "Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase," Nat. Struct. Mol. Biol. 14 (8), 689-695 (2007). DOI: 10.1038/nsmb1273

Brian A. Moore, Howard H. Robinson, Zhaohui Xu, "The Crystal Structure of Mouse Exo70 Reveals Unique Features of the Mammalian Exocyst," J. Mol. Biol. 371 (2), 410-421 (2007). DOI: 10.1016/j.jmb.2007.05.018

Matthew H. Sazinsky, Benjamin LeMoine, Maria Orofino, Roman Davydov, Krisztina Z. Bencze, Timothy L. Stemmler, Brian M. Hoffman, Jose M. Arguello, Amy C. Rosenzweig, "Characterization and Structure of a Zn[superscript 2+] and [2Fe-2S]-containing Copper Chaperone from Archaeoglobus fulgidus," J. Biol. Chem. 282 (35), 25950-25959 (2007). DOI: 10.1074/jbc.M703311200

Debra S. Touw, Christer E. Nordman, Jeanne A. Stuckey, Vincent L. Pecoraro, "Identifying important structural characteristics of arsenic resistance proteins by using designed three-stranded coiled coils," Proc. Natl. Acad. Sci. USA 104 (29), 11969-11974 (2007). DOI: 10.1073/pnas.0701979104

Chi-Lin Tsai, Kuppan Gokulan, Pablo Sobrado, James C. Sacchettini, Paul F. Fitzpatrick, "Mechanistic and Structural Studies of H373Q Flavocytochrome b[subscript 2]:  Effects of Mutating the Active Site Base," Biochemistry-US 46 (26), 7844-7851 (2007). DOI: 10.1021/bi7005543

Scott A. Lujan, Laura M. Guogas, Heather Ragonese, Steven W. Matson, Matthew R. Redinbo, "Disrupting antibiotic resistance propagation by inhibiting the conjugative DNA relaxase," Proc. Natl. Acad. Sci. USA 104 (30), 12282-12287 (2007). DOI: 10.1073/pnas.0702760104

Jeremiah S. Joseph, Kumar Singh Saikatendu, Vanitha Subramanian, Benjamin W. Neuman, Michael J. Buchmeier, Raymond C. Stevens, Peter Kuhn, "Crystal Structure of a Monomeric Form of Severe Acute Respiratory Syndrome Coronavirus Endonuclease nsp15 Suggests a Role for Hexamerization as an Allosteric Switch," J. Virol. 81 (12), 6700-6708 (2007). DOI: 10.1128/JVI.02817-06

Sanghamitra Dey, Zhiqin Hu, Xiao Lan Xu, James C. Sacchettini, Gregory A. Grant, "The Effect of Hinge Mutations on Effector Binding and Domain Rotation in Escherichia coli D-3-Phosphoglycerate Dehydrogenase," J. Biol. Chem. 282 (25), 18418-18426 (2007). DOI: 10.1074/jbc.M701174200

Sergey Stepanov, "Transformation of X-ray Server from a set of WWW-accessed programs into WWW-based library for remote calls from X-ray data analysis software," Thin Solid Films 515 (14), 5700-5703 (2007). DOI: 10.1016/j.tsf.2006.12.011

Feng Wang, Robert Langley, Gulcin Gulten, Lei Wang, James C. Sacchettini, "Identification of a Type III Thioesterase Reveals the Function of an Operon Crucial for Mtb Virulence," Chem. Biol. 14 (5), 543-551 (2007). DOI: 10.1016/j.chembiol.2007.04.005

Ling Qin, Denise A. Mills, Carrie Hiser, Anna Murphree, R. Michael Garavito, Shelagh Ferguson-Miller, Jonathan Hosler, "Crystallographic Location and Mutational Analysis of Zn and Cd Inhibitory Sites and Role of Lipidic Carboxylates in Rescuing Proton Path Mutants in Cytochrome c Oxidase," Biochemistry-US 46 (21), 6239-6248 (2007). DOI: 10.1021/bi700173w

Erik W. Debler, Gunnar F. Kaufmann, Robert N. Kirchdoerfer, Jenny M. Mee, Kim D. Janda, Ian A. Wilson, "Crystal structures of a quorum-quenching antibody," J. Mol. Biol. 368 (5), 1392-1402 (2007). DOI: 10.1016/j.jmb.2007.02.081

M. Rossmann, "Fellow of the American Academy of Microbiology," (2007).

Arati Ramesh, Christos G. Savva, Andreas Holzenburg, James C. Sacchettini, "Crystal Structure of Rsr, an Ortholog of the Antigenic Ro Protein, Links Conformational Flexibility to RNA Binding Activity," J. Biol. Chem. 282 (20), 14960-14967 (2007). DOI: 10.1074/jbc.M611163200

C. Gerdts, "The Elizabeth R. Norton Prize at the University of Chicago," (2007).

S. Yan, G. Gawlak, K. Makabe, V. Tereshko, A. Koide, S. Koide, "Hydrophobic Surface Burial Is the Major Stability Determinant of a Flat, Single-layer [beta]-Sheet," J. Mol. Biol. 368 (1), 230-243 (2007). DOI: 10.1016/j.jmb.2007.02.003

Korin E. Wheeler, Judith M. Nocek, Deborah A. Cull, Liliya A. Yatsunyk, Amy C. Rosenzweig, Brian M. Hoffman, "Dynamic Docking of Cytochrome b[subscript 5] with Myoglobin and [alpha]-Hemoglobin: Heme-Neutralization “Squares” and the Binding of Electron-Transfer-Reactive Configurations," J. Am. Chem. Soc. 129 (13), 3906-3917 (2007). DOI: 10.1021/ja067598g

Akiko Koide, Ryan N. Gilbreth, Kaori Esaki, Valentina Tereshko, Shohei Koide, "High-affinity single-domain binding proteins with a binary-code interface," Proc. Natl. Acad. Sci. USA 104 (16), 6632-6637 (2007). DOI: 10.1073/pnas.0700149104

Sergei P. Boudko, Richard J. Kuhn, Michael G. Rossmann, "The Coiled-coil Domain Structure of the Sin Nombre Virus Nucleocapsid Protein," J. Mol. Biol. 366 (5), 1538-1544 (2007). DOI: 10.1016/j.jmb.2006.12.046

Mihwa Lee, Megan J. Maher, J. Mitchell Guss, "Structure of the T109S mutant of Escherichia coli dihydroorotase complexed with the inhibitor 5-­fluoroorotate: catalytic activity is reflected by the crystal form," Acta Crystallogr. F 63 (3), 154-161 (2007). DOI: 10.1107/S1744309107004009

N.P. Coussens, J.C. Mowers, C. McDonald, G. Nunez, S. Ramaswamy, "Crystal structure of the Nod1 caspase activation and recruitment domain," Biochem. Biophys. Res. Commun. 353 (1), 1-5 (2007). DOI: 10.1016/j.bbrc.2006.11.122

Raquel L. Lieberman, Brandon A. Wustman, Pedro Huertas, Allan C. Powe Jr, Corey W. Pine, Richie Khanna, Michael G. Schlossmacher, Dagmar Ringe, Gregory A. Petsko, "Structure of acid [beta]-glucosidase with pharmacological chaperone provides insight into Gaucher disease," Nat. Chem. Biol. 3 (2), 101-107 (2007). DOI: 10.1038/nchembio850

Vladimir Yu. Torbeev, Stephen B.H. Kent, "Convergent Chemical Synthesis and Crystal Structure of a 203 Amino Acid 'Covalent Dimer' HIV-1 Protease Enzyme Molecule," Angew. Chem. Int. Ed. 43 (10), 1667-1670 (2007). DOI: 10.1002/anie.200604087

S. Ferguson-Miller, "American Association for the Advancement of Science," (2007).

Feng Wang, Elaine R. Podell, Arthur J. Zaug, Yuting Yang, Paul Baciu, Thomas R. Cech, Ming Lei, "The POT1–TPP1 telomere complex is a telomerase processivity factor," Nature 445, 506-510 (2007). DOI: 10.1038/nature05454

Consuelo Garcia-Rodriguez, Raphael Levy, Joseph W. Arndt, Charles M. Forsyth, Ali Razai, Jianlong Lou, Isin Geren, Raymond C. Stevens, James D. Marks, "Molecular evolution of antibody cross-reactivity for two subtypes of type A botulinum neurotoxin," Nat. Biotechnol. 25 (1), 107-116 (2007). DOI: 10.1038/nbt1269

Eduard Bitto, Craig A. Bingman, Gary E. Wesenberg, Jason G. McCoy, George N. Phillips, Jr., "Structure of aspartoacylase, the brain enzyme impaired in Canavan disease," Proc. Natl. Acad. Sci. USA 104 (2), 456-461 (2007). DOI: 10.1073/pnas.0607817104

Pierre Aller, Mark A. Rould, Matthew Hogg, Susan S. Wallace, Sylvie Doublie´, "A structural rationale for stalling of a replicative DNA polymerase at the most common oxidative thymine lesion, thymine glycol," Proc. Natl. Acad. Sci. USA 104 (3), 814-818 (2007). DOI: 10.1073/pnas.0606648104

Feng Wang, Robert Langley, Gulcin Gulten, Lynn G. Dover, Gurdyal S. Besra, William R. Jacobs, Jr., James C. Sacchettini, "Mechanism of thioamide drug action against tuberculosis and leprosy," J. Exp. Med. 204 (1), 73-78 (2007). DOI: 10.1084/jem.20062100

Matthew Hogg, Pierre Aller, William Konigsberg, Susan S. Wallace, Sylvie Doublie, "Structural and Biochemical Investigation of the Role in Proofreading of a [beta] Hairpin Loop Found in the Exonuclease Domain of a Replicative DNA Polymerase of the B Family," J. Biol. Chem. 282 (2), 1432-1444 (2007). DOI: 10.1074/jbc.M605675200

Koki Makabe, Valentina Tereshko, Grzegorz Gawlak, Shude Yan, Shohei Koide, "Atomic-resolution crystal structure of Borrelia burgdorferi outer surface protein A via surface engineering," Protein Sci. 15, 1907-1914 (2006). DOI: 10.1110/ps.062246706

Y. Xiang, M.C. Morais, A.J. Battisti, S. Grimes, P.J. Jardine, D.L. Anderson, M.G. Rossmann, "Structural changes of bacteriophage [phi]29 upon DNA packaging and release," EMBO J. 25, 5229-5239 (2006). DOI: 10.1038/sj.emboj.7601386

Catherine Vilchèze, Feng Wang, Masayoshi Arai, Manzour Hernando Hazbón, Roberto Colangeli, Laurent Kremer, Torin R. Weisbrod, David Alland, James C. Sacchettini, William R . Jacobs, Jr, "Transfer of a point mutation in Mycobacterium tuberculosis inhA resolves the target of isoniazid," Nat. Med. 12, 1027-1029 (2006). DOI: 10.1038/nm1466

Cory J. Gerdts, Valentina Tereshko, Maneesh K. Yadav, Irina Dementieva, Frank Collart, Andrzej Joachimiak, Raymond C. Stevens, Peter Kuhn, Anthony Kossiakoff, Rustem F. Ismagilov, "Time-Controlled Microfluidic Seeding in nL-Volume Droplets To Separate Nucleation and Growth Stages of Protein Crystallization," Angew. Chem. Int. Ed. 45 (48), 8156-8160 (2006). DOI: 10.1002/anie.200602946

Quansheng Liu, Jaclyn C. Greimann, Christopher D. Lima, "Reconstitution, Activities, and Structure of the Eukaryotic RNA Exosome," Cell 127 (6), 1223-1237 (2006). DOI: 10.1016/j.cell.2006.10.037

Liang Li, Debarshi Mustafi, Qiang Fu, Valentina Tereshko, Delai L. Chen, Joshua D. Tice, Rustem F. Ismagilov, "Nanoliter microfluidic hybrid method for simultaneous screening and optimization validated with crystallization of membrane proteins," Proc. Natl. Acad. Sci. USA 103 (51), 19243-19248 (2006). DOI: 10.1073/pnas.0607502103

Lu Gan, Jeffrey A. Speir, James F. Conway, Gabriel Lander, Naiqian Cheng, Brian A. Firek, Roger W. Hendrix, Robert L. Duda, Lars Liljas, John E. Johnson, "Capsid Conformational Sampling in HK97 Maturation Visualized by X-Ray Crystallography and Cryo-EM," Structure 14 (11), 1655-1665 (2006). DOI: 10.1016/j.str.2006.09.006

Koki Makabe, Dan McElheny, Valentia Tereshko, Aaron Hilyard, Grzegorz Gawlak, Shude Yan, Akiko Koide, Shohei Koide, "Atomic structures of peptide self-assembly mimics," Proc. Natl. Acad. Sci. USA 103 (47), 17753-17758 (2006). DOI: 10.1073/pnas.0606690103

Peng R. Chen, Taeok Bae, Wade A. Williams, Erica M. Duguid, Phoebe A. Rice, Olaf Schneewind, Chuan He, "An oxidation-sensing mechanism is used by the global regulator MgrA in Staphylococcus aureus," Nat. Chem. Biol. 2 (11), 591-595 (2006). DOI: 10.1038/nchembio820

S.G. Podorov, N.N. Faleev, K.M. Pavlov, D.M. Paganin, S.A. Stepanov, E. Förster, "A new approach to wide-angle dynamical X-ray diffraction by deformed crystals," J. Appl. Crystallogr. 39 (5), 652-655 (2006). DOI: 10.1107/S0021889806025696

Susan J. Gagnon, Oleg Y. Borbulevych, Rebecca L. Davis-Harrison, Richard V. Turner, Marale Damirjian, Alison Wojnarowicz, William E. Biddison, Brian M. Baker, "T Cell Receptor Recognition via Cooperative Conformational Plasticity," J. Mol. Biol. 363 (1), 228-243 (2006). DOI: 10.1016/j.jmb.2006.08.045

John W. Giraldes, David L. Akey, Jeffrey D. Kittendorf, David H. Sherman, Janet L. Smith, Robert A. Fecik, "Structural and mechanistic insights into polyketide macrolactonization from polyketide-based affinity labels," Nat. Chem. Biol. 2 (10), 531-536 (2006). DOI: 10.1038/nchembio822

Ling Qin, Carrie Hiser, Anne Mulichak, R. Michael Garavito, Shelagh Ferguson-Miller, "Identification of conserved lipid/detergent-binding sites in a high-resolution structure of the membrane protein cytochrome c oxidase," Proc. Natl. Acad. Sci. USA 103 (44), 16117-16122 (2006). DOI: 10.1073/pnas.0606149103

David L. Akey, Jeffrey D. Kittendorf, John W. Giraldes, Robert A. Fecik, David H. Sherman, Janet L. Smith, "Structural basis for macrolactonization by the pikromycin thioesterase," Nat. Chem. Biol. 2 (10), 537-542 (2006). DOI: 10.1038/nchembio824

Yong Chen, Yuting Yang, Feng Wang, Ke Wan, Kenichi Yamane, Yi Zhang, Ming Lei, "Crystal structure of human histone lysine-specific demethylase 1 (LSD1)," Proc. Natl. Acad. Sci. USA 103 (38), 13956-13961 (2006). DOI: 10.1073/pnas.0606381103

Jill E. Chrencik, Alexei Brooun, Michelle L. Kraus, Michael I. Recht, Anand R. Kolatkar, Gye Won Han, Jan Marcus Seifert, Hans Widmer, Manfred Auer, Peter Kuhn, "Structural and Biophysical Characterization of the EphB4·EphrinB2 Protein-Protein Interaction and Receptor Specificity," J. Biol. Chem. 281 (38), 28185-28192 (2006). DOI: 10.1074/jbc.M605766200

J.G. McCoy, C.A. Bingman, E. Bitto, M.M. Holdorf, C.A. Makaroff, G. N. Phillips Jr., "Structure of an ETHE1-like protein from Arabidopsis thaliana," Acta Crystallogr. D 62 (9), 964-970 (2006). DOI: 10.1107/S0907444906020592

Jeremiah S. Joseph, Kumar Singh Saikatendu, Vanitha Subramanian, Benjamin W. Neuman, Alexei Brooun, Mark Griffith, Kin Moy, Maneesh K. Yadav, Jeffrey Velasquez, Michael J. Buchmeier, Raymond C. Stevens, Peter Kuhn, "Crystal Structure of Nonstructural Protein 10 from the Severe Acute Respiratory Syndrome Coronavirus Reveals a Novel Fold with Two Zinc-Binding Motifs," J. Virol. 80 (16), 7894-7901 (2006). DOI: 10.1128/JVI.00467-06

Kevin G. Hoff, Jose L. Avalos, Kristin Sens, Cynthia Wolberger, "Insights into the Sirtuin Mechanism from Ternary Complexes Containing NAD[superscript +] and Acetylated Peptide," Structure 14 (8), 1231-1240 (2006). DOI: 10.1016/j.str.2006.06.006

Matthew H. Sazinsky, Sorabh Agarwal, Jose M. Arguello, Amy C. Rosenzweig, "Structure of the actuator domain from the Archaeoglobus fulgidus Cu[superscript +]-ATPase," Biochemistry-US 45 (33), 9949-9955 (2006). DOI: 10.1021/bi0610045

Haitao Li, Serge Ilin, Wooikoon Wang, Elizabeth M. Duncan, Joanna Wysocka, C. David Allis, Dinshaw J. Patel, "Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF," Nature 442, 91-95 (2006). DOI: 10.1038/nature04802

Tao Wang, Xiangbin Zhang, Poonam Bheda, Javier R. Revollo, Shin-ichiro Imai, Cynthia Wolberger, "Structure of Nampt/PBEF/visfatin, a mammalian NAD[superscript +]biosynthetic enzyme," Nat. Struct. Mol. Biol. 13 (7), 661-662 (2006). DOI: 10.1038/nsmb1114

Kiira Ratia, Kumar Singh Saikatendu, Bernard D. Santarsiero, Naina Barretto, Susan C. Baker, Raymond C. Stevens, Andrew D. Mesecar, "Severe acute respiratory syndrome coronavirus papain-like protease: Structure of a viral deubiquitinating enzyme," Proc. Natl. Acad. Sci. USA 103 (15), 5717-5722 (2006). DOI: 10.1073/pnas.0510851103

Chittaranjan Das, Quyen Q. Hoang, Cheryl A. Kreinbring, Sarah J. Luchansky, Robin K. Meray, Soumya S. Ray, Peter T. Lansbury, Dagmar Ringe, Gregory A. Petsko, "Structural basis for conformational plasticity of the Parkinson's disease-associated ubiquitin hydrolase UCH-L1," Proc. Natl. Acad. Sci. USA 103 (12), 4675-4680 (2006). DOI: 10.1073/pnas.0510403103

Jason G. McCoy, Lucas J. Bailey, Eduard Bitto, Craig A. Bingman, David J. Aceti, Brian G. Fox, George N. Phillips Jr., "Structure and mechanism of mouse cysteine dioxygenase," Proc. Natl. Acad. Sci. USA 103 (9), 3084-3089 (2006). DOI: 10.1073/pnas.0509262103

I.H. Solomon, J.M. Hager, R. Safi, D.P. McDonnell, M.R. Redinbo, E.A. Ortlund, "Crystal structure of the human LRH-1 DBD-DNA complex reveals Ftz-F1 domain positioning is required for receptor activity," J. Mol. Biol. 354 (5), 1091-1102 (2005).

Eduard Bitto, Craig A. Bingman, Jason G. McCoy, Simon T.M. Allard, Gary E. Wesenberg, George N. Phillips Jr., "The structure at 1.6 Å resolution of the protein product of the At4g34215 gene from Arabidopsis thaliana," Acta Crystallogr. D 61 (12), 1655-1661 (2005). DOI: 10.1107/S0907444905034074

Maneesh K. Yadav, Cory J. Gerdts, Ruslan Sanishvili, Ward W. Smith, L. Spencer Roach, Rustem F. Ismagilov, Peter Kuhn, Raymond C. Stevens, "In situ data collection and structure refinement from microcapillary protein crystallization," J. Appl. Crystallogr. 38 (6), 900-905 (2005).

Kumar Singh Saikatendu, Jeremiah S. Joseph, Vanitha Subramanian, Tom Clayton, Mark Griffith, Kin Moy, Jeffrey Velasquez, Benjamin W. Neuman, Michael J. Buchmeier, Raymond C. Stevens, Peter Kuhn, "Structural Basis of Severe Acute Respiratory Syndrome Coronavirus ADP-Ribose-1´´-Phosphate Dephosphorylation by a Conserved Domain of nsP3," Structure 13, 1665-1675 (2005). DOI: 10.1016/j.str.2005.07.022

L. Gan, "Best Poster Award, Molecular Biology/Molecular & Experimental Medicine, Society of Fellows 2005 Fall Poster Symposium," (2005).

Jinhua Wu, Aloke K. Bera, Richard J. Kuhn, Janet L. Smith, "Structure of the Flavivirus Helicase: Implications for Catalytic Activity, Protein Interactions, and Proteolytic Processing," J. Virol. 79 (16), 10268-10277 (2005). DOI: 10.1128/JVI.79.16.10268-10277.2005

J.W. Arndt, W. Yu, F. Bi, R.C. Stevens, "Crystal structure of botulinum neurotoxin type G light chain: serotype divergence in substrate recognition," Biochemistry-US 44 (28), 9574-9580 (2005). DOI: 10.1021/bi0505924

Simon T.M. Allard, Craig A. Bingman, Kenneth A. Johnson, Gary E. Wesenberg, Eduard Bitto, WonBae Jeon, George N. Phillips Jr., "Structure at 1.6 Å resolution of the protein from gene locus At3g22680 from Arabidopsis thaliana," Acta Crystallogr. F 61 (7), 647-650 (2005). DOI: 10.1107/S1744309105019743

Maneesh K. Yadav, James E. Redman, Luke J. Leman, Julietta M. Alvarez-Gutierrez, Yanming Zhang, C. David Stout, M. Reza Ghadiri, "Structure-Based Engineering of Internal Cavities in Coiled-Coil Peptides," Biochemistry-US 44 (28), 9723-9732 (2005). DOI: 10.1021/bi050742a

S. Xu, R.F. Fischetti, "A Ray-Tracing Study of the Dependence of Focal Properties on Surface Figure Error for a Kirkpatrick-Baez (K-B) Mirror System," American Institute of Physics, 705, AIP (2004), 776 - 779.

Sergey Stepanov, "How to make X-ray simulation software working on WWW: A simple recipe based on seven years of experience," Advances in Computational Methods for X-Ray and Neutron Optics, Manuel Sanchez del Rio, ed., 5536, SPIE (2004), 165 - 170.

S. Stepanov, "X-ray server: an online resource for simulations of X-ray diffraction and scattering," Advances in Computational Methods for X-ray and Neutron Optics, Manuel Sanchez del Rio, ed., 5536, SPIE (2004), 16 - 26.

J.T. Collins, C.L. Doose, J.N. Attig, M.M. Baehl, "Canted-undulator front-end exit-mask flow-induced vibration measurements," LS-306, (November -2004).


Number of Records: 1293


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